The service catalogue, which has been developed within the CORBEL project, is the first tool to list the main services of all LS-RIs at a glance and it aims to facilitate the utilisation of RI services by researchers from all over the world, providing a basic overview on existing services within distinct thematic fields.
You can either use the service catalogue to identify a single RI to help you with your work or you can create a service pipeline, i.e. using several RIs simultaneously.
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AnaEE-ERIC (Analysis and Experimentation on Ecosystems) operates a pan-European network of experimental ecology facilities open to the scientific community and stakeholders. We apply the full scientific experimental method—modelling, manipulating, measuring. This fosters scientific innovation and develop evidence-based solutions for ecosystem protection and climate adaptation strategies.
Services: Open-air and Enclosed facilities for terrestrial and aquatic ecosystems / Analytical facilities, laboratories, remote sensing, and advanced measurements / Data & Modelling facilities for data interpretation
Costs: Prices depend on the nature of the service and are available upon request.
Access modes: Access can be physical, remote or virtual, depending on the type of service requested.
Why AnaEE: With AnaEE, researchers can conduct experimental research in a wide range of ecosystems throughout Europe (including overseas) and combine it with analytical and modelling services.
Countries involved: BE, BG, CZ, DK, FI, FR, IT, CIHEAM
Contact person: contact@anaee.eu
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IBISBA is a European infrastructure that uniquely produces translational R&D&I services to an international community of industrial biotechnology stakeholders. IBISBA simplifies access to advanced multidisciplinary services that accelerate end-to-end bioprocess development and contributes to the delivery of low carbon, low environmental footprint technologies for a wide variety of market sectors.
Services: Protein discovery and engineering / Production strain development / Bioprocess development and optimisation / Omnics and analytics / TEA,LCA
Costs: Access can be subsidised for selected users who apply for Transnational Access Calls. All costs can be covered, depending on funds availability and project quality. Co-funding (user financial participation) can be requested in case user projects exceed the subsidy ceiling fixed by the IBISBA’s TNA programme. Alternatively, access can be paid and the costs depend on the type of services requested.
Access modes: Access can be on-site, remote (mail-in samples) or virtual (digital tools). Europe-wide access to integrated platforms operating multidisciplinary services is currently under development and clients will benefit from a single-entry point to the IBISBA R&D services. Two types of access will be offered: Collaborative R&D Services: Services that involve beyond state-of-the-art research and development activities that move science/technology along the pathway to innovation. For these services, IBISBA guarantees work quality, but not results. Standard Integrated Services: Propose state-of-the-art, standardised services with a guarantee of the quality of results.
Why IBISBA: Researchers across the private and public sectors will benefit from single access to best-in-class faciliities and capabilities processing unique know-how and operational excellence across Europe, thus reducing regional and national inequalities. Finding a comprehensive service offer no longer requires endless, multi-contact searchers. IBISBA will work with users to identify the right combination of services to suit their R&D needs.
Countries involved: BE, DE, ES, FI, FR, GR, IT, NL, UK
Contact person: Michael O’Donohue, michael.odonohue@inrae.fr
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BBMRI-ERIC is a research infrastructure of biobanks and biomolecular resources. The main goal is to provide expertise and services, advancing the use of European sample collections and its data for the benefit of human health. The activities are on a non-economic basis and primarily intended for member countries.
Services: BBMRI-ERIC delivers services to their member states in IT; Quality Management; ELSI; Biobanking Development; Public Affairs; and Outreach, Education and Communications
Costs: Services are free for those biobanks that are located in a member state.
Access modes: Access can be on-site or online, dependent on the requested service.
Why BBMRI-ERIC: Reproducible data in research is key and in order to achieve that, you need high-quality samples and data as a starting point. BBMRI-ERIC enables biobanks to work with high-quality samples and associated data and supports controlled access to the wider research community, being a true gateway to health.
Countries involved: Members: AT, BE, BG, CH, CY, CZ, DE, EE, ES, FI, GR, HU, IT, LT, LV, ML, NL, NO, PL, SE, SK, SL / Observers: DK, IARC/WHO, QA, TR
Contact person: Eleanor Shember, contact@bbmri-eric.eu
The following RIs offer complementary services
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EATRIS is the European infrastructure for translational medicine. The infrastructure brings together resources and services for research communities to translate scientific discoveries into benefits for patients.
Services: Support funding applications (Identification of partners for consortium building, assessment of the project plan’s impact and innovation potential) / Translational research facilities and expertise for development of novel biomarkers, diagnostics and therapeutics / Molecular, functional & hybrid imaging technologies, preclinical models, samples, patient cohorts, GMP manufacturing / Regulatory and Health Technology Assessment (HTA) expertise / Advice on intellectual property issues and industry partnering strategy (innovation management)
Costs: Costs are calculated on a case by case basis depending on the service required; some services can also be provided as part of funding proposals with EATRIS joining consortia as partner or subcontractor.
Access modes: Services performed can be offered either centrally by the coordination and support team based in Amsterdam or remotely by the EATRIS institutions.
Why EATRIS: Translating novel biology insights into effective interventions or medical applications is a highly complex process. It requires significant dedicated expertise, facilities and resources. We believe in your medical innovation and we want to support you by bringing together the multi-disciplinary expertise and infrastructure required for optimising your translational trajectory. Working with EATRIS gives greater confidence in the translational feasibility of your project and its impact.
Countries involved: FR, NL, CZ, HR, SE, NO, FI, IT, ES, SI, LU, LV, PO, BG
Contact person: Florence Bietrix
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The European Marine Biological Research Centre (EMBRC-ERIC) is a Research Infrastructure including 29 Operators across 9 different European countries. EMBRC is dedicated for marine biology and ecology research. EMBRC offers to the scientific community, academic institutions and private companies a comprehensive set of services to study marine organisms and to give access to ecosystems. EMBRC is providing local or remote access to state-of-the-art national facilities such as renowned marine biological stations.
Services: Access to ecosystems / Marine biological resources (micro & macro, alive & fixed, wild & cultivated) / Experimental facilities / Technology platforms / E-Infrastructure, Data & services / Supporting facilities
Costs: Prices depend on the nature of the service and are available upon request.
Access modes: Through the 29 European operators, users can access the services remotely or on-site. The user has to select the service of interest, submit a proposal and he/she will receive feedback or be contacted.
Why EMBRC: Researchers should contact us in order to have access to marine ecosystems, marine biological resources and associated technological platforms for analysis.
Countries involved: BE, ES, FR, IT, GR, NO, PT, IL, UK
Contact person: info@embrc.eu
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INFRAFRONTIER is the European research infrastructure for the development, phenotyping, archiving and distribution of model mammalian genomes. It is formed by more than 25 research centres in 14 European countries and Canada. In INFRAFRONTIER these partners join forces to commonly advance the basic understanding of human health and disease using mouse and rodent models.
Services: Archiving and distribution of scientifically valuable mutant mouse strains / Rodent model development (mouse and rat) using gene targeting in embryonic ES-cells or CRISPR/CAS9 technologies/ Systemic phenotyping of mutant mice for a whole-organism view on gene function / Germ-free (axenic) mice/ Validated genetically engineered mouse models of cancer / Access to comprehensinve expertise and training
Costs: Some of the INFRAFRONTIER resources and services are provided free of charge, others entail user fees to recover costs. There are periodic Open Calls to fund researchers, for detailed information see the INFRAFRONTIER website.
Access modes: Access modalities vary with the kind of resource or service requested.
Why INFRAFRONTIER: INFRAFRONTIER provides access to unique resources and expertise to advance the understanding of human health and disease using mammalian models. Our users can rely on highest quality standards and long-standing experience. INFRAFRONTIER’s one-stop-shop facilitates efficient research.
Countries involved: DE, GR, FI, CZ, FR, EMBL
Contact person: INFRAFRONTIER Scientific User Support
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MIRRI is the pan-European research infrastructure for microbial resources [i.e. bacteria (including cyanobacteria), archaea, fungi, yeasts, plant viruses, bacteriophages and their isolated DNA]. In addition, the MIRRI repertoire also covers human, animal and plant cell cultures. By provision of high quality microorganisms, associated data and the broad expertise of our partners, MIRRI aims to support research and development in the field of biotechnology.
Services: Access to microorganisms/cell lines deposited in public collections / deposit of microorganisms/cell lines (public collection/patents) / phenotypic/molecular characterisation of microorganisms / identification/molecular typing of microorganisms / isolation/cultivation/preservation of microorganisms / microbial community analyses / microbial phylogenetic studies / screening/bioassays with / microorganisms / access to microbiological databases / consultancy/contract research / legal issues (e.g. Nagoya Protocol) / biosafety/biosecurity / training
Costs: Costs depend on the kind of service requested.
Access modes: Access modes depend on the kind of service requested.
Why MIRRI: MIRRI offers not only a broad spectrum of high quality microorganisms, but also a longlasting expertise in each field of microbiology. Aiming at harmonising the current microbial Biological Resource Centre (mBRC) landscape, MIRRI enables facilitated access to deposited microorganisms and is constantly improving the corresponding state-of-the-art service offers. Our experts ensure legal compliance of resources (Nagoya Protocol) and with the envisaged interoperability of existing and future databases researchers can exploit the full value of microorganisms.
Countries involved: Under development
Contact person: MIRRI Interim Secretariat
The following RIs offer complementary services
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ERINHA is a pan-European distributed life sciences research Infrastructure dedicated to the study of highly infectious emerging and re-emerging high-consequence pathogens (RG4 & unknown). It brings together leading European high containment and complementary research facilities and expertise required to perform cutting-edge research on highly infectious diseases. ERINHA provides access to its state of art BSL-4 laboratories and complementary capacities and expertise to perform excellence orientated in-vitro and in-vivo research projects, trainings and advise. A wide range of capabilities and functions from high basic research laboratory capacities to NHP modeling research are provided by ERINHA, as well as expertise of senior scientists and access to complementary functions (from BSL1 to BSL4, genomics, proteomics etc.). ERINHA produces the ideal environment to facilitate coordination of research on high-consequence pathogens in Europe. The infrastructure will contribute to the enhancement of the European and global capacity, capability and emergency preparedness in the response to global outbreaks. Since 2018, ERINHA has been granted landmark status by the European Strategy Forum on Research Infrastructures (ESFRI).
Services: Access to state of art European high containment (BSL4 & BSL3) and complementary facilities to advance research on high-consequence pathogens / In-vivo testing with a variety of animal models (including small rodents, ferrets, and non-human primates) / In-vitro experiments using highly pathogenic agents with both in-person and remote access possibilities. / Project coordination and management of large scale research programmes on high consequence pathogens / Training (General Biosecurity Training; Operations of a Biosafety Laboratory; Training for potential users) / Advice and scientific expertise provider (RG4 pathogens research, containment facilities construction, biosafety/biosecurity issues, sample transport etc.) / Access to pathogens specimens
Costs: For access costs information contact ERINHA Central Coordinating Unit (CCU) at contact@erinha.eu
Access modes: ERINHA provides in-person and remote access to its services. Projects can be submitted by academic, public and industrial users. For more information contact ERINHA CCU at contact@erinha.eu
Why ERINHA: The 2014-2015 Ebola outbreak and cases in Europe demonstrated the worldwide vulnerability and need for common action putting together rare high containment capacities and expertise to be able to increase European and global preparedness for outbreaks of high consequence pathogens. ERINHA facilitates access to required infrastructure capacities thanks to its CCU and multiple high containment and complementary European resources. It is a unique coordinated infrastrucuture providing transnational access to its facilities, large scope of services and shorter delays in access.
Countries involved: Austria (Medical University of Graz), Belgium (KUL), France (Inserm), Hungary (Ministry of Human Capacities), Netherlands (ERASMUS MC), Portugal (INSA), Spain (Instituto de Salud Carlos III), Sweden (FOHM)
Contact person: Diana Stepanyan-Yerdamian, Dylan Bonfils, contact@erinha.eu
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EU-OPENSCREEN integrates high-capacity screening platforms throughout Europe, which jointly use a rationally selected compound collection, comprising up to 140.000 commercial and proprietary compounds collected from European chemists. EU-OPENSCREEN offers to researchers from academic institutions, SMEs and industrial organisations open access to its shared resources. EU-OPENSCREEN will collaboratively develop novel molecular tool compounds with external users from various disciplines of the life sciences.
Services: High-throughput compound/ drug screening (HTS) / access to a unique European compound collection (> 100,000 compounds) / assay adaption / chemical optimization and profiling of preliminary ‘hits’ / bioprofiling of donated compounds / provision of standardised data / training and education activities
Costs: A screening project at a typical EU-OPENSCREEN screening site will cost 50-250k €, strongly depending on the number of screened substances and the maturity/ complexity of the assay. A compound replenishment fee structure applies to all projects using the EU-OPENSCREEN compound collection and users from countries which are members of the EU-OPENSCREEN ERIC will receive a discount on this cost.
Access modes: Users are requested to submit project proposal to the EU-OPENSCREEN office. Depending on the project requirements, the RI can be assessed remotely or on-site.
Why EU-OPENSCREEN: The majority of scientists in Europe do not have access to suitable technology platforms and compound collections, which are generally expensive to purchase, operate and maintain. As a large-scale research infrastructure (RI) with an ‘open’ pre-competitive character, EU-OPENSCREEN will cost-effectively overcome this limitation by: involving and providing access to Europe’s leading screening platforms and chemistry groups; offering a jointly used rationally designed compound collection; and operating an open-access bioactivity database which will be accessible on a global basis. EU-OPENSCREEN offers to support you through grant application processes and beyond for funding involving screening projects.
Countries involved: CZ, FI, DE, LV, NO, PO, ES, DK
Contact person: Project Manager: Dr. Tanja Miletic
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ELIXIR unites Europe’s leading life science organisations in managing and safeguarding the increasing volume of data being generated by publicly funded research. It coordinates, integrates and sustains bioinformatics resources across its member states and enables users in academia and industry to access services that are vital for their research.
Services: Databases / tools / Interoperibility services / Computing facilities / Training courses
Costs: Whilst there may be a charge for accessing some national compute facilities, the majority of services are free for users. For example, depositing and accessing data from databases is free, as are training courses, interoperiblity services and tools for the analsyis of data. For further information please contact us.
Access modes: Users access the services virtually (online) and directly with the resource they are interested in. No application to or access via the ELIXIR Hub is required.
Why ELIXIR: ELIXIR coordinates and develops life science resources across Europe so that researchers can more easily find, analyse and share data, exchange expertise, and implement best practices. This makes it possible for them to gain greater insights into how living organisms work.
Countries involved: EMBL, UK, SE, CH, CZ, EE, NO, NL, DK, IL, PT, FI, FR, ES, BE, IT, SI, LU, IE, DE, HU, GR / Observers: CY, AT, RO
Contact person: Andy Smith
The following RIs offer complementary services
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BBMRI-ERIC is a research infrastructure of biobanks and biomolecular resources. The main goal is to provide expertise and services, advancing the use of European sample collections and its data for the benefit of human health. The activities are on a non-economic basis and primarily intended for member countries.
Services: BBMRI-ERIC delivers services to their member states in IT; Quality Management; ELSI; Biobanking Development; Public Affairs; and Outreach, Education and Communications
Costs: Services are free for those biobanks that are located in a member state.
Access modes: Access can be on-site or online, dependent on the requested service.
Why BBMRI-ERIC: Reproducible data in research is key and in order to achieve that, you need high-quality samples and data as a starting point. BBMRI-ERIC enables biobanks to work with high-quality samples and associated data and supports controlled access to the wider research community, being a true gateway to health.
Countries involved: Members: AT, BE, BG, CH, CY, CZ, DE, EE, ES, FI, GR, HU, IT, LT, LV, ML, NL, NO, PL, SE, SK, SL / Observers: DK, IARC/WHO, QA, TR
Contact person: Eleanor Shember, contact@bbmri-eric.eu
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ECRIN is a pan-European distributed infrastructure that links scientific partners across Europe to facilitate multinational clinical research. ECRIN provides sponsors and investigators with support for the development and implementation of multinational clinical trials.
Services: Information and advice for funding applications and preparation of multinational clinical trials (methodology, operational aspects, regulatory, ethics, contracting…) / Trial management operations (interaction with competent authorities & ethics committees, project management, monitoring, vigilance, data management) / Clinical trial tools (outcome measures, regulatory database, site locations, risk-based monitoring) / Data centre certification program (audits European, non-commercial data centres using ECRIN IT/DM standards, to confirm their ability to provide compliant, effective, and efficient data management services for controlled clinical trials)
Costs: Information and advice are free for ECRIN members. The cost of trial management services depends on the type of service requested. Data centre certification costs depend on the type of country membership.
Access modes: Users submit their proposal or request to ECRIN office; the access mode depends on proposal and needs. There are annual calls for data centre certification.
Why ECRIN: Difficulties in locating clinical trials units, fulfilling local legal, regulatory and ethical requirements, and coordinating multi-country clinical trial management deter many researchers from attempting multinational clinical trials. This means that most independent clinical trials are conducted in single centres, or multiple centres within one country. ECRIN provides a path through Europe’s fragmented health and legal systems with its pan-European infrastructure that is designed to support multinational clinical research and unlock access to patients and medical expertise.
Countries involved: FR, DE, HU, IT, NO, ES, PT, CZ, IE / Observers: CH, SK, PL
Contact person: Christine Kubiak, christine.kubiak@ecrin.org
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The European Marine Biological Research Centre (EMBRC-ERIC) is a Research Infrastructure including 29 Operators across 9 different European countries. EMBRC is dedicated for marine biology and ecology research. EMBRC offers to the scientific community, academic institutions and private companies a comprehensive set of services to study marine organisms and to give access to ecosystems. EMBRC is providing local or remote access to state-of-the-art national facilities such as renowned marine biological stations.
Services: Access to ecosystems / Marine biological resources (micro & macro, alive & fixed, wild & cultivated) / Experimental facilities / Technology platforms / E-Infrastructure, Data & services / Supporting facilities
Costs: Prices depend on the nature of the service and are available upon request.
Access modes: Through the 29 European operators, users can access the services remotely or on-site. The user has to select the service of interest, submit a proposal and he/she will receive feedback or be contacted.
Why EMBRC: Researchers should contact us in order to have access to marine ecosystems, marine biological resources and associated technological platforms for analysis.
Countries involved: BE, ES, FR, IT, GR, NO, PT, IL, UK
Contact person: info@embrc.eu
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EMPHASIS is a pan-European, distributed plant phenotyping infrastructure. EMPHASIS will focus on developing and enabling access to plant phenotyping infrastructure and provision of services essential for the analysis of crop performance with respect to structure, function, quality and interaction with the environment. It will thus support the exploitation of crop genetic diversity required for the enhancement of plant productivity and progress in plant breeding.
Services: In cooperation with EPPN2020, EMPHASIS offers access to plant phenotyping infrastructures, which includes high-throughput facilities / lean field facilities / intensive field facilities / assay development / data management
Costs: European-wide access to plant phenotyping infrastructures is currently under development in our partner project EPPN2020 and is provided via its homepage. Access will be accordingly provided by EMPHASIS once it reaches its operational phase.
Access modes: Through the 29 European operators, users can access the services remotely or on-site. The user has to select the service of interest, submit a proposal and he/she will receive feedback or be contacted.
Why EMPHASIS: EPPN2020 provides transnational access to plant phenotyping infrastructure as a basis for novel scientific approaches to quantitative plant assessment in high throughput. The installations represent a diverse set of facilities for plant phenotyping in Europe with focus on: i) non-invasive high-throughput phenotyping under controlled conditions, ii) destructive sampling aiming at assessing underlying traits helping to understand the genetic variability of different plant processes, iii) controlled field facilities allowing users to control rainfall and/or the concentration of air CO2 together with high-definition, non-invasive sensors. Transnational access will be available based on a simple and transparent access procedure.
Countries involved: Preparatory phase of the project: BE, FR, IT, NL, UK, DE
Contact person: Dr. Roland Pieruschka, Dr. Sven Fahrner
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EU-OPENSCREEN integrates high-capacity screening platforms throughout Europe, which jointly use a rationally selected compound collection, comprising up to 140.000 commercial and proprietary compounds collected from European chemists. EU-OPENSCREEN offers to researchers from academic institutions, SMEs and industrial organisations open access to its shared resources. EU-OPENSCREEN will collaboratively develop novel molecular tool compounds with external users from various disciplines of the life sciences.
Services: High-throughput compound/ drug screening (HTS) / access to a unique European compound collection (> 100,000 compounds) / assay adaption / chemical optimization and profiling of preliminary ‘hits’ / bioprofiling of donated compounds / provision of standardised data / training and education activities
Costs: A screening project at a typical EU-OPENSCREEN screening site will cost 50-250k €, strongly depending on the number of screened substances and the maturity/ complexity of the assay. A compound replenishment fee structure applies to all projects using the EU-OPENSCREEN compound collection and users from countries which are members of the EU-OPENSCREEN ERIC will receive a discount on this cost.
Access modes: Users are requested to submit project proposal to the EU-OPENSCREEN office. Depending on the project requirements, the RI can be assessed remotely or on-site.
Why EU-OPENSCREEN: The majority of scientists in Europe do not have access to suitable technology platforms and compound collections, which are generally expensive to purchase, operate and maintain. As a large-scale research infrastructure (RI) with an ‘open’ pre-competitive character, EU-OPENSCREEN will cost-effectively overcome this limitation by: involving and providing access to Europe’s leading screening platforms and chemistry groups; offering a jointly used rationally designed compound collection; and operating an open-access bioactivity database which will be accessible on a global basis. EU-OPENSCREEN offers to support you through grant application processes and beyond for funding involving screening projects.
Countries involved: CZ, FI, DE, LV, NO, PO, ES, DK
Contact person: Project Manager: Dr. Tanja Miletic
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Euro-BioImaging offers life scientists open access to imaging instruments, expertise, training opportunities, and data management services that they do not find at their home institutions or among their collaboration partners. All scientists, regardless of affiliation, area of expertise, or field of activity, can benefit from these pan-European open access services.
Services: Euro-BioImaging offers state-of-the-art imaging services through its internationally renowned facilities, called Nodes. Nodes cover the whole spectrum of biological and biomedical imaging, with an ever-growing portfolio of cutting-edge instruments. Researchers at any stage of their career can request access to over 45+ imaging technologies hosted at 33 Nodes located in 16 European countries and at EMBL. New technologies are included continuously to offer access to the most innovative and pioneering technologies on the market.
Costs: The access fees for each visit are individually discussed and agreed upon directly between the Euro-BioImaging user and the respective Euro-BioImaging Node as part of the pre-visit discussion during the project planning phase. The user is therefore fully informed of all costs that will arise related to the access to a Euro-BioImaging Node. The Euro-BioImaging Hub, taking care of all administrative work in Euro-BioImaging, do not charge any costs to the users! Access support for users is announced on the Euro-BioImaging Web Portal.
Access modes: Euro-BioImaging offers open access to its technology portfolio, which is put in place using a selection procedure based on scientific soundness and technical feasibility of the project. In most cases, scientists visit the requested Node to perform their experiments on-site, being supported throughout their project by expert technical staff. Access to the image data resources are remote, online and can be found via the Euro-BioImaging Web Portal.
Why Euro-BioImaging: All scientists, regardless of affiliation, area of expertise, or field of activity, can benefit from Euro-BioImaging’s pan-European open access services. For most technologies, scientists are invited to receive hands-on training at the imaging instrument of their choice so that they can generate the desired data sets themselves and expand their technological knowledge. Visits can vary in length between single days to several weeks or months, depending on the project’s need and individual circumstances. Scientists interested in accessing Euro BioImaging services simply submit a short description of their planned experiment via the online application portal. Senior scientists and Node staff will offer expert advice on the project’s scope and experimental set-up to ensure that the experiment has the best chance of success from the very first visit.
Countries involved: Austria, Bulgaria, Czech Republic, Denmark, Finland, France, Hungary, Israel, Italy , Norway, Poland, Portugal, Slovenia, Sweden, The Netherlands, United Kingdom, EMBL (intergovernmental organisation), Belgium (observer)
Contact person: Johanna Bischof, Alessandra Viale
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Instruct-ERIC is a pan-European research infrastructure in structural biology, making high-end technologies and methods available to scientists. Access is provided free for academic scientists at Instruct centres and includes expert support.
Services: Sample Preparation (Crystallisation, Nanobody Discovery, Protein Production) / Biomolecular Analysis (Imaging, Mass Spectrometry, Molecular Biophysics) / 3D Structural Analysis (Electron Microscopy, Magnetic Resonance Techniques, X-ray Techniques) / Compuational Services for Structural Biology (Bioinformatics Tools, Integrative Modelling, Crystallography, Electron Microscopy, NMR)
Costs: Free for academic users; on service-basis for commercial use (user access is on a fee for service basis; no obligation to disclose or publish data). Users can apply for travel and accommodation costs where a physical visit to an Instruct facility is required.
Access modes: Depending on the requested service, access can be on-site, remote, or mail-in sample.
Why Instruct-ERIC: Instruct is at the cutting edge of new technologies: automation, remote access, new detector methods, advanced imaging. Access to Instruct-ERIC infrastructure can help advance your research – more than 1200 peer-reviewed scientific publications acknowledge Instruct.
Countries involved: BE, CZ, EMBL, FI, FR, DE, GR, IL, IT, LV, LT, NL, PT, SK, SI, ES, UK
Contact person: Dr. Claudia Alen Amaro, Coordinator Head of Operations
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MIRRI is the pan-European research infrastructure for microbial resources [i.e. bacteria (including cyanobacteria), archaea, fungi, yeasts, plant viruses, bacteriophages and their isolated DNA]. In addition, the MIRRI repertoire also covers human, animal and plant cell cultures. By provision of high quality microorganisms, associated data and the broad expertise of our partners, MIRRI aims to support research and development in the field of biotechnology.
Services: Access to microorganisms/cell lines deposited in public collections / deposit of microorganisms/cell lines (public collection/patents) / phenotypic/molecular characterisation of microorganisms / identification/molecular typing of microorganisms / isolation/cultivation/preservation of microorganisms / microbial community analyses / microbial phylogenetic studies / screening/bioassays with / microorganisms / access to microbiological databases / consultancy/contract research / legal issues (e.g. Nagoya Protocol) / biosafety/biosecurity / training
Costs: Costs depend on the kind of service requested.
Access modes: Access modes depend on the kind of service requested.
Why MIRRI: MIRRI offers not only a broad spectrum of high quality microorganisms, but also a longlasting expertise in each field of microbiology. Aiming at harmonising the current microbial Biological Resource Centre (mBRC) landscape, MIRRI enables facilitated access to deposited microorganisms and is constantly improving the corresponding state-of-the-art service offers. Our experts ensure legal compliance of resources (Nagoya Protocol) and with the envisaged interoperability of existing and future databases researchers can exploit the full value of microorganisms.
Countries involved: Under development
Contact person: MIRRI Interim Secretariat
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ECRIN is a pan-European distributed infrastructure that links scientific partners across Europe to facilitate multinational clinical research. ECRIN provides sponsors and investigators with support for the development and implementation of multinational clinical trials.
Services: Information and advice for funding applications and preparation of multinational clinical trials (methodology, operational aspects, regulatory, ethics, contracting…) / Trial management operations (interaction with competent authorities & ethics committees, project management, monitoring, vigilance, data management) / Clinical trial tools (outcome measures, regulatory database, site locations, risk-based monitoring) / Data centre certification program (audits European, non-commercial data centres using ECRIN IT/DM standards, to confirm their ability to provide compliant, effective, and efficient data management services for controlled clinical trials)
Costs: Information and advice are free for ECRIN members. The cost of trial management services depends on the type of service requested. Data centre certification costs depend on the type of country membership.
Access modes: Users submit their proposal or request to ECRIN office; the access mode depends on proposal and needs. There are annual calls for data centre certification.
Why ECRIN: Difficulties in locating clinical trials units, fulfilling local legal, regulatory and ethical requirements, and coordinating multi-country clinical trial management deter many researchers from attempting multinational clinical trials. This means that most independent clinical trials are conducted in single centres, or multiple centres within one country. ECRIN provides a path through Europe’s fragmented health and legal systems with its pan-European infrastructure that is designed to support multinational clinical research and unlock access to patients and medical expertise.
Countries involved: FR, DE, HU, IT, NO, ES, PT, CZ, IE / Observers: CH, SK, PL
Contact person: Christine Kubiak, christine.kubiak@ecrin.org
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BBMRI-ERIC is a research infrastructure of biobanks and biomolecular resources. The main goal is to provide expertise and services, advancing the use of European sample collections and its data for the benefit of human health. The activities are on a non-economic basis and primarily intended for member countries.
Services: BBMRI-ERIC delivers services to their member states in IT; Quality Management; ELSI; Biobanking Development; Public Affairs; and Outreach, Education and Communications
Costs: Services are free for those biobanks that are located in a member state.
Access modes: Access can be on-site or online, dependent on the requested service.
Why BBMRI-ERIC: Reproducible data in research is key and in order to achieve that, you need high-quality samples and data as a starting point. BBMRI-ERIC enables biobanks to work with high-quality samples and associated data and supports controlled access to the wider research community, being a true gateway to health.
Countries involved: Members: AT, BE, BG, CH, CY, CZ, DE, EE, ES, FI, GR, HU, IT, LT, LV, ML, NL, NO, PL, SE, SK, SL / Observers: DK, IARC/WHO, QA, TR
Contact person: Eleanor Shember, contact@bbmri-eric.eu
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ECRIN is a pan-European distributed infrastructure that links scientific partners across Europe to facilitate multinational clinical research. ECRIN provides sponsors and investigators with support for the development and implementation of multinational clinical trials.
Services: Information and advice for funding applications and preparation of multinational clinical trials (methodology, operational aspects, regulatory, ethics, contracting…) / Trial management operations (interaction with competent authorities & ethics committees, project management, monitoring, vigilance, data management) / Clinical trial tools (outcome measures, regulatory database, site locations, risk-based monitoring) / Data centre certification program (audits European, non-commercial data centres using ECRIN IT/DM standards, to confirm their ability to provide compliant, effective, and efficient data management services for controlled clinical trials)
Costs: Information and advice are free for ECRIN members. The cost of trial management services depends on the type of service requested. Data centre certification costs depend on the type of country membership.
Access modes: Users submit their proposal or request to ECRIN office; the access mode depends on proposal and needs. There are annual calls for data centre certification.
Why ECRIN: Difficulties in locating clinical trials units, fulfilling local legal, regulatory and ethical requirements, and coordinating multi-country clinical trial management deter many researchers from attempting multinational clinical trials. This means that most independent clinical trials are conducted in single centres, or multiple centres within one country. ECRIN provides a path through Europe’s fragmented health and legal systems with its pan-European infrastructure that is designed to support multinational clinical research and unlock access to patients and medical expertise.
Countries involved: FR, DE, HU, IT, NO, ES, PT, CZ, IE / Observers: CH, SK, PL
Contact person: Christine Kubiak, christine.kubiak@ecrin.org
The following RIs offer complementary services
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EATRIS is the European infrastructure for translational medicine. The infrastructure brings together resources and services for research communities to translate scientific discoveries into benefits for patients.
Services: Support funding applications (Identification of partners for consortium building, assessment of the project plan’s impact and innovation potential) / Translational research facilities and expertise for development of novel biomarkers, diagnostics and therapeutics / Molecular, functional & hybrid imaging technologies, preclinical models, samples, patient cohorts, GMP manufacturing / Regulatory and Health Technology Assessment (HTA) expertise / Advice on intellectual property issues and industry partnering strategy (innovation management)
Costs: Costs are calculated on a case by case basis depending on the service required; some services can also be provided as part of funding proposals with EATRIS joining consortia as partner or subcontractor.
Access modes: Services performed can be offered either centrally by the coordination and support team based in Amsterdam or remotely by the EATRIS institutions.
Why EATRIS: Translating novel biology insights into effective interventions or medical applications is a highly complex process. It requires significant dedicated expertise, facilities and resources. We believe in your medical innovation and we want to support you by bringing together the multi-disciplinary expertise and infrastructure required for optimising your translational trajectory. Working with EATRIS gives greater confidence in the translational feasibility of your project and its impact.
Countries involved: FR, NL, CZ, HR, SE, NO, FI, IT, ES, SI, LU, LV, PO, BG
Contact person: Florence Bietrix
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EATRIS is the European infrastructure for translational medicine. The infrastructure brings together resources and services for research communities to translate scientific discoveries into benefits for patients.
Services: Support funding applications (Identification of partners for consortium building, assessment of the project plan’s impact and innovation potential) / Translational research facilities and expertise for development of novel biomarkers, diagnostics and therapeutics / Molecular, functional & hybrid imaging technologies, preclinical models, samples, patient cohorts, GMP manufacturing / Regulatory and Health Technology Assessment (HTA) expertise / Advice on intellectual property issues and industry partnering strategy (innovation management)
Costs: Costs are calculated on a case by case basis depending on the service required; some services can also be provided as part of funding proposals with EATRIS joining consortia as partner or subcontractor.
Access modes: Services performed can be offered either centrally by the coordination and support team based in Amsterdam or remotely by the EATRIS institutions.
Why EATRIS: Translating novel biology insights into effective interventions or medical applications is a highly complex process. It requires significant dedicated expertise, facilities and resources. We believe in your medical innovation and we want to support you by bringing together the multi-disciplinary expertise and infrastructure required for optimising your translational trajectory. Working with EATRIS gives greater confidence in the translational feasibility of your project and its impact.
Countries involved: FR, NL, CZ, HR, SE, NO, FI, IT, ES, SI, LU, LV, PO, BG
Contact person: Florence Bietrix
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ECRIN is a pan-European distributed infrastructure that links scientific partners across Europe to facilitate multinational clinical research. ECRIN provides sponsors and investigators with support for the development and implementation of multinational clinical trials.
Services: Information and advice for funding applications and preparation of multinational clinical trials (methodology, operational aspects, regulatory, ethics, contracting…) / Trial management operations (interaction with competent authorities & ethics committees, project management, monitoring, vigilance, data management) / Clinical trial tools (outcome measures, regulatory database, site locations, risk-based monitoring) / Data centre certification program (audits European, non-commercial data centres using ECRIN IT/DM standards, to confirm their ability to provide compliant, effective, and efficient data management services for controlled clinical trials)
Costs: Information and advice are free for ECRIN members. The cost of trial management services depends on the type of service requested. Data centre certification costs depend on the type of country membership.
Access modes: Users submit their proposal or request to ECRIN office; the access mode depends on proposal and needs. There are annual calls for data centre certification.
Why ECRIN: Difficulties in locating clinical trials units, fulfilling local legal, regulatory and ethical requirements, and coordinating multi-country clinical trial management deter many researchers from attempting multinational clinical trials. This means that most independent clinical trials are conducted in single centres, or multiple centres within one country. ECRIN provides a path through Europe’s fragmented health and legal systems with its pan-European infrastructure that is designed to support multinational clinical research and unlock access to patients and medical expertise.
Countries involved: FR, DE, HU, IT, NO, ES, PT, CZ, IE / Observers: CH, SK, PL
Contact person: Christine Kubiak, christine.kubiak@ecrin.org
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ERINHA is a pan-European distributed life sciences research Infrastructure dedicated to the study of highly infectious emerging and re-emerging high-consequence pathogens (RG4 & unknown). It brings together leading European high containment and complementary research facilities and expertise required to perform cutting-edge research on highly infectious diseases. ERINHA provides access to its state of art BSL-4 laboratories and complementary capacities and expertise to perform excellence orientated in-vitro and in-vivo research projects, trainings and advise. A wide range of capabilities and functions from high basic research laboratory capacities to NHP modeling research are provided by ERINHA, as well as expertise of senior scientists and access to complementary functions (from BSL1 to BSL4, genomics, proteomics etc.). ERINHA produces the ideal environment to facilitate coordination of research on high-consequence pathogens in Europe. The infrastructure will contribute to the enhancement of the European and global capacity, capability and emergency preparedness in the response to global outbreaks. Since 2018, ERINHA has been granted landmark status by the European Strategy Forum on Research Infrastructures (ESFRI).
Services: Access to state of art European high containment (BSL4 & BSL3) and complementary facilities to advance research on high-consequence pathogens / In-vivo testing with a variety of animal models (including small rodents, ferrets, and non-human primates) / In-vitro experiments using highly pathogenic agents with both in-person and remote access possibilities. / Project coordination and management of large scale research programmes on high consequence pathogens / Training (General Biosecurity Training; Operations of a Biosafety Laboratory; Training for potential users) / Advice and scientific expertise provider (RG4 pathogens research, containment facilities construction, biosafety/biosecurity issues, sample transport etc.) / Access to pathogens specimens
Costs: For access costs information contact ERINHA Central Coordinating Unit (CCU) at contact@erinha.eu
Access modes: ERINHA provides in-person and remote access to its services. Projects can be submitted by academic, public and industrial users. For more information contact ERINHA CCU at contact@erinha.eu
Why ERINHA: The 2014-2015 Ebola outbreak and cases in Europe demonstrated the worldwide vulnerability and need for common action putting together rare high containment capacities and expertise to be able to increase European and global preparedness for outbreaks of high consequence pathogens. ERINHA facilitates access to required infrastructure capacities thanks to its CCU and multiple high containment and complementary European resources. It is a unique coordinated infrastrucuture providing transnational access to its facilities, large scope of services and shorter delays in access.
Countries involved: Austria (Medical University of Graz), Belgium (KUL), France (Inserm), Hungary (Ministry of Human Capacities), Netherlands (ERASMUS MC), Portugal (INSA), Spain (Instituto de Salud Carlos III), Sweden (FOHM)
Contact person: Diana Stepanyan-Yerdamian, Dylan Bonfils, contact@erinha.eu
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MIRRI is the pan-European research infrastructure for microbial resources [i.e. bacteria (including cyanobacteria), archaea, fungi, yeasts, plant viruses, bacteriophages and their isolated DNA]. In addition, the MIRRI repertoire also covers human, animal and plant cell cultures. By provision of high quality microorganisms, associated data and the broad expertise of our partners, MIRRI aims to support research and development in the field of biotechnology.
Services: Access to microorganisms/cell lines deposited in public collections / deposit of microorganisms/cell lines (public collection/patents) / phenotypic/molecular characterisation of microorganisms / identification/molecular typing of microorganisms / isolation/cultivation/preservation of microorganisms / microbial community analyses / microbial phylogenetic studies / screening/bioassays with / microorganisms / access to microbiological databases / consultancy/contract research / legal issues (e.g. Nagoya Protocol) / biosafety/biosecurity / training
Costs: Costs depend on the kind of service requested.
Access modes: Access modes depend on the kind of service requested.
Why MIRRI: MIRRI offers not only a broad spectrum of high quality microorganisms, but also a longlasting expertise in each field of microbiology. Aiming at harmonising the current microbial Biological Resource Centre (mBRC) landscape, MIRRI enables facilitated access to deposited microorganisms and is constantly improving the corresponding state-of-the-art service offers. Our experts ensure legal compliance of resources (Nagoya Protocol) and with the envisaged interoperability of existing and future databases researchers can exploit the full value of microorganisms.
Countries involved: Under development
Contact person: MIRRI Interim Secretariat
The following RIs offer complementary services
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The European Marine Biological Research Centre (EMBRC-ERIC) is a Research Infrastructure including 29 Operators across 9 different European countries. EMBRC is dedicated for marine biology and ecology research. EMBRC offers to the scientific community, academic institutions and private companies a comprehensive set of services to study marine organisms and to give access to ecosystems. EMBRC is providing local or remote access to state-of-the-art national facilities such as renowned marine biological stations.
Services: Access to ecosystems / Marine biological resources (micro & macro, alive & fixed, wild & cultivated) / Experimental facilities / Technology platforms / E-Infrastructure, Data & services / Supporting facilities
Costs: Prices depend on the nature of the service and are available upon request.
Access modes: Through the 29 European operators, users can access the services remotely or on-site. The user has to select the service of interest, submit a proposal and he/she will receive feedback or be contacted.
Why EMBRC: Researchers should contact us in order to have access to marine ecosystems, marine biological resources and associated technological platforms for analysis.
Countries involved: BE, ES, FR, IT, GR, NO, PT, IL, UK
Contact person: info@embrc.eu
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EATRIS is the European infrastructure for translational medicine. The infrastructure brings together resources and services for research communities to translate scientific discoveries into benefits for patients.
Services: Support funding applications (Identification of partners for consortium building, assessment of the project plan’s impact and innovation potential) / Translational research facilities and expertise for development of novel biomarkers, diagnostics and therapeutics / Molecular, functional & hybrid imaging technologies, preclinical models, samples, patient cohorts, GMP manufacturing / Regulatory and Health Technology Assessment (HTA) expertise / Advice on intellectual property issues and industry partnering strategy (innovation management)
Costs: Costs are calculated on a case by case basis depending on the service required; some services can also be provided as part of funding proposals with EATRIS joining consortia as partner or subcontractor.
Access modes: Services performed can be offered either centrally by the coordination and support team based in Amsterdam or remotely by the EATRIS institutions.
Why EATRIS: Translating novel biology insights into effective interventions or medical applications is a highly complex process. It requires significant dedicated expertise, facilities and resources. We believe in your medical innovation and we want to support you by bringing together the multi-disciplinary expertise and infrastructure required for optimising your translational trajectory. Working with EATRIS gives greater confidence in the translational feasibility of your project and its impact.
Countries involved: FR, NL, CZ, HR, SE, NO, FI, IT, ES, SI, LU, LV, PO, BG
Contact person: Florence Bietrix
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EU-OPENSCREEN integrates high-capacity screening platforms throughout Europe, which jointly use a rationally selected compound collection, comprising up to 140.000 commercial and proprietary compounds collected from European chemists. EU-OPENSCREEN offers to researchers from academic institutions, SMEs and industrial organisations open access to its shared resources. EU-OPENSCREEN will collaboratively develop novel molecular tool compounds with external users from various disciplines of the life sciences.
Services: High-throughput compound/ drug screening (HTS) / access to a unique European compound collection (> 100,000 compounds) / assay adaption / chemical optimization and profiling of preliminary ‘hits’ / bioprofiling of donated compounds / provision of standardised data / training and education activities
Costs: A screening project at a typical EU-OPENSCREEN screening site will cost 50-250k €, strongly depending on the number of screened substances and the maturity/ complexity of the assay. A compound replenishment fee structure applies to all projects using the EU-OPENSCREEN compound collection and users from countries which are members of the EU-OPENSCREEN ERIC will receive a discount on this cost.
Access modes: Users are requested to submit project proposal to the EU-OPENSCREEN office. Depending on the project requirements, the RI can be assessed remotely or on-site.
Why EU-OPENSCREEN: The majority of scientists in Europe do not have access to suitable technology platforms and compound collections, which are generally expensive to purchase, operate and maintain. As a large-scale research infrastructure (RI) with an ‘open’ pre-competitive character, EU-OPENSCREEN will cost-effectively overcome this limitation by: involving and providing access to Europe’s leading screening platforms and chemistry groups; offering a jointly used rationally designed compound collection; and operating an open-access bioactivity database which will be accessible on a global basis. EU-OPENSCREEN offers to support you through grant application processes and beyond for funding involving screening projects.
Countries involved: CZ, FI, DE, LV, NO, PO, ES, DK
Contact person: Project Manager: Dr. Tanja Miletic
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The European Marine Biological Research Centre (EMBRC-ERIC) is a Research Infrastructure including 29 Operators across 9 different European countries. EMBRC is dedicated for marine biology and ecology research. EMBRC offers to the scientific community, academic institutions and private companies a comprehensive set of services to study marine organisms and to give access to ecosystems. EMBRC is providing local or remote access to state-of-the-art national facilities such as renowned marine biological stations.
Services: Access to ecosystems / Marine biological resources (micro & macro, alive & fixed, wild & cultivated) / Experimental facilities / Technology platforms / E-Infrastructure, Data & services / Supporting facilities
Costs: Prices depend on the nature of the service and are available upon request.
Access modes: Through the 29 European operators, users can access the services remotely or on-site. The user has to select the service of interest, submit a proposal and he/she will receive feedback or be contacted.
Why EMBRC: Researchers should contact us in order to have access to marine ecosystems, marine biological resources and associated technological platforms for analysis.
Countries involved: BE, ES, FR, IT, GR, NO, PT, IL, UK
Contact person: info@embrc.eu
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ERINHA is a pan-European distributed life sciences research Infrastructure dedicated to the study of highly infectious emerging and re-emerging high-consequence pathogens (RG4 & unknown). It brings together leading European high containment and complementary research facilities and expertise required to perform cutting-edge research on highly infectious diseases. ERINHA provides access to its state of art BSL-4 laboratories and complementary capacities and expertise to perform excellence orientated in-vitro and in-vivo research projects, trainings and advise. A wide range of capabilities and functions from high basic research laboratory capacities to NHP modeling research are provided by ERINHA, as well as expertise of senior scientists and access to complementary functions (from BSL1 to BSL4, genomics, proteomics etc.). ERINHA produces the ideal environment to facilitate coordination of research on high-consequence pathogens in Europe. The infrastructure will contribute to the enhancement of the European and global capacity, capability and emergency preparedness in the response to global outbreaks. Since 2018, ERINHA has been granted landmark status by the European Strategy Forum on Research Infrastructures (ESFRI).
Services: Access to state of art European high containment (BSL4 & BSL3) and complementary facilities to advance research on high-consequence pathogens / In-vivo testing with a variety of animal models (including small rodents, ferrets, and non-human primates) / In-vitro experiments using highly pathogenic agents with both in-person and remote access possibilities. / Project coordination and management of large scale research programmes on high consequence pathogens / Training (General Biosecurity Training; Operations of a Biosafety Laboratory; Training for potential users) / Advice and scientific expertise provider (RG4 pathogens research, containment facilities construction, biosafety/biosecurity issues, sample transport etc.) / Access to pathogens specimens
Costs: For access costs information contact ERINHA Central Coordinating Unit (CCU) at contact@erinha.eu
Access modes: ERINHA provides in-person and remote access to its services. Projects can be submitted by academic, public and industrial users. For more information contact ERINHA CCU at contact@erinha.eu
Why ERINHA: The 2014-2015 Ebola outbreak and cases in Europe demonstrated the worldwide vulnerability and need for common action putting together rare high containment capacities and expertise to be able to increase European and global preparedness for outbreaks of high consequence pathogens. ERINHA facilitates access to required infrastructure capacities thanks to its CCU and multiple high containment and complementary European resources. It is a unique coordinated infrastrucuture providing transnational access to its facilities, large scope of services and shorter delays in access.
Countries involved: Austria (Medical University of Graz), Belgium (KUL), France (Inserm), Hungary (Ministry of Human Capacities), Netherlands (ERASMUS MC), Portugal (INSA), Spain (Instituto de Salud Carlos III), Sweden (FOHM)
Contact person: Diana Stepanyan-Yerdamian, Dylan Bonfils, contact@erinha.eu
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MIRRI is the pan-European research infrastructure for microbial resources [i.e. bacteria (including cyanobacteria), archaea, fungi, yeasts, plant viruses, bacteriophages and their isolated DNA]. In addition, the MIRRI repertoire also covers human, animal and plant cell cultures. By provision of high quality microorganisms, associated data and the broad expertise of our partners, MIRRI aims to support research and development in the field of biotechnology.
Services: Access to microorganisms/cell lines deposited in public collections / deposit of microorganisms/cell lines (public collection/patents) / phenotypic/molecular characterisation of microorganisms / identification/molecular typing of microorganisms / isolation/cultivation/preservation of microorganisms / microbial community analyses / microbial phylogenetic studies / screening/bioassays with / microorganisms / access to microbiological databases / consultancy/contract research / legal issues (e.g. Nagoya Protocol) / biosafety/biosecurity / training
Costs: Costs depend on the kind of service requested.
Access modes: Access modes depend on the kind of service requested.
Why MIRRI: MIRRI offers not only a broad spectrum of high quality microorganisms, but also a longlasting expertise in each field of microbiology. Aiming at harmonising the current microbial Biological Resource Centre (mBRC) landscape, MIRRI enables facilitated access to deposited microorganisms and is constantly improving the corresponding state-of-the-art service offers. Our experts ensure legal compliance of resources (Nagoya Protocol) and with the envisaged interoperability of existing and future databases researchers can exploit the full value of microorganisms.
Countries involved: Under development
Contact person: MIRRI Interim Secretariat
The following RIs offer complementary services
-
EMPHASIS is a pan-European, distributed plant phenotyping infrastructure. EMPHASIS will focus on developing and enabling access to plant phenotyping infrastructure and provision of services essential for the analysis of crop performance with respect to structure, function, quality and interaction with the environment. It will thus support the exploitation of crop genetic diversity required for the enhancement of plant productivity and progress in plant breeding.
Services: In cooperation with EPPN2020, EMPHASIS offers access to plant phenotyping infrastructures, which includes high-throughput facilities / lean field facilities / intensive field facilities / assay development / data management
Costs: European-wide access to plant phenotyping infrastructures is currently under development in our partner project EPPN2020 and is provided via its homepage. Access will be accordingly provided by EMPHASIS once it reaches its operational phase.
Access modes: Through the 29 European operators, users can access the services remotely or on-site. The user has to select the service of interest, submit a proposal and he/she will receive feedback or be contacted.
Why EMPHASIS: EPPN2020 provides transnational access to plant phenotyping infrastructure as a basis for novel scientific approaches to quantitative plant assessment in high throughput. The installations represent a diverse set of facilities for plant phenotyping in Europe with focus on: i) non-invasive high-throughput phenotyping under controlled conditions, ii) destructive sampling aiming at assessing underlying traits helping to understand the genetic variability of different plant processes, iii) controlled field facilities allowing users to control rainfall and/or the concentration of air CO2 together with high-definition, non-invasive sensors. Transnational access will be available based on a simple and transparent access procedure.
Countries involved: Preparatory phase of the project: BE, FR, IT, NL, UK, DE
Contact person: Dr. Roland Pieruschka, Dr. Sven Fahrner
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EU-OPENSCREEN integrates high-capacity screening platforms throughout Europe, which jointly use a rationally selected compound collection, comprising up to 140.000 commercial and proprietary compounds collected from European chemists. EU-OPENSCREEN offers to researchers from academic institutions, SMEs and industrial organisations open access to its shared resources. EU-OPENSCREEN will collaboratively develop novel molecular tool compounds with external users from various disciplines of the life sciences.
Services: High-throughput compound/ drug screening (HTS) / access to a unique European compound collection (> 100,000 compounds) / assay adaption / chemical optimization and profiling of preliminary ‘hits’ / bioprofiling of donated compounds / provision of standardised data / training and education activities
Costs: A screening project at a typical EU-OPENSCREEN screening site will cost 50-250k €, strongly depending on the number of screened substances and the maturity/ complexity of the assay. A compound replenishment fee structure applies to all projects using the EU-OPENSCREEN compound collection and users from countries which are members of the EU-OPENSCREEN ERIC will receive a discount on this cost.
Access modes: Users are requested to submit project proposal to the EU-OPENSCREEN office. Depending on the project requirements, the RI can be assessed remotely or on-site.
Why EU-OPENSCREEN: The majority of scientists in Europe do not have access to suitable technology platforms and compound collections, which are generally expensive to purchase, operate and maintain. As a large-scale research infrastructure (RI) with an ‘open’ pre-competitive character, EU-OPENSCREEN will cost-effectively overcome this limitation by: involving and providing access to Europe’s leading screening platforms and chemistry groups; offering a jointly used rationally designed compound collection; and operating an open-access bioactivity database which will be accessible on a global basis. EU-OPENSCREEN offers to support you through grant application processes and beyond for funding involving screening projects.
Countries involved: CZ, FI, DE, LV, NO, PO, ES, DK
Contact person: Project Manager: Dr. Tanja Miletic
The following RIs offer complementary services
-
EATRIS is the European infrastructure for translational medicine. The infrastructure brings together resources and services for research communities to translate scientific discoveries into benefits for patients.
Services: Support funding applications (Identification of partners for consortium building, assessment of the project plan’s impact and innovation potential) / Translational research facilities and expertise for development of novel biomarkers, diagnostics and therapeutics / Molecular, functional & hybrid imaging technologies, preclinical models, samples, patient cohorts, GMP manufacturing / Regulatory and Health Technology Assessment (HTA) expertise / Advice on intellectual property issues and industry partnering strategy (innovation management)
Costs: Costs are calculated on a case by case basis depending on the service required; some services can also be provided as part of funding proposals with EATRIS joining consortia as partner or subcontractor.
Access modes: Services performed can be offered either centrally by the coordination and support team based in Amsterdam or remotely by the EATRIS institutions.
Why EATRIS: Translating novel biology insights into effective interventions or medical applications is a highly complex process. It requires significant dedicated expertise, facilities and resources. We believe in your medical innovation and we want to support you by bringing together the multi-disciplinary expertise and infrastructure required for optimising your translational trajectory. Working with EATRIS gives greater confidence in the translational feasibility of your project and its impact.
Countries involved: FR, NL, CZ, HR, SE, NO, FI, IT, ES, SI, LU, LV, PO, BG
Contact person: Florence Bietrix
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EMPHASIS is a pan-European, distributed plant phenotyping infrastructure. EMPHASIS will focus on developing and enabling access to plant phenotyping infrastructure and provision of services essential for the analysis of crop performance with respect to structure, function, quality and interaction with the environment. It will thus support the exploitation of crop genetic diversity required for the enhancement of plant productivity and progress in plant breeding.
Services: In cooperation with EPPN2020, EMPHASIS offers access to plant phenotyping infrastructures, which includes high-throughput facilities / lean field facilities / intensive field facilities / assay development / data management
Costs: European-wide access to plant phenotyping infrastructures is currently under development in our partner project EPPN2020 and is provided via its homepage. Access will be accordingly provided by EMPHASIS once it reaches its operational phase.
Access modes: Through the 29 European operators, users can access the services remotely or on-site. The user has to select the service of interest, submit a proposal and he/she will receive feedback or be contacted.
Why EMPHASIS: EPPN2020 provides transnational access to plant phenotyping infrastructure as a basis for novel scientific approaches to quantitative plant assessment in high throughput. The installations represent a diverse set of facilities for plant phenotyping in Europe with focus on: i) non-invasive high-throughput phenotyping under controlled conditions, ii) destructive sampling aiming at assessing underlying traits helping to understand the genetic variability of different plant processes, iii) controlled field facilities allowing users to control rainfall and/or the concentration of air CO2 together with high-definition, non-invasive sensors. Transnational access will be available based on a simple and transparent access procedure.
Countries involved: Preparatory phase of the project: BE, FR, IT, NL, UK, DE
Contact person: Dr. Roland Pieruschka, Dr. Sven Fahrner
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Instruct-ERIC is a pan-European research infrastructure in structural biology, making high-end technologies and methods available to scientists. Access is provided free for academic scientists at Instruct centres and includes expert support.
Services: Sample Preparation (Crystallisation, Nanobody Discovery, Protein Production) / Biomolecular Analysis (Imaging, Mass Spectrometry, Molecular Biophysics) / 3D Structural Analysis (Electron Microscopy, Magnetic Resonance Techniques, X-ray Techniques) / Compuational Services for Structural Biology (Bioinformatics Tools, Integrative Modelling, Crystallography, Electron Microscopy, NMR)
Costs: Free for academic users; on service-basis for commercial use (user access is on a fee for service basis; no obligation to disclose or publish data). Users can apply for travel and accommodation costs where a physical visit to an Instruct facility is required.
Access modes: Depending on the requested service, access can be on-site, remote, or mail-in sample.
Why Instruct-ERIC: Instruct is at the cutting edge of new technologies: automation, remote access, new detector methods, advanced imaging. Access to Instruct-ERIC infrastructure can help advance your research – more than 1200 peer-reviewed scientific publications acknowledge Instruct.
Countries involved: BE, CZ, EMBL, FI, FR, DE, GR, IL, IT, LV, LT, NL, PT, SK, SI, ES, UK
Contact person: Dr. Claudia Alen Amaro, Coordinator Head of Operations
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MIRRI is the pan-European research infrastructure for microbial resources [i.e. bacteria (including cyanobacteria), archaea, fungi, yeasts, plant viruses, bacteriophages and their isolated DNA]. In addition, the MIRRI repertoire also covers human, animal and plant cell cultures. By provision of high quality microorganisms, associated data and the broad expertise of our partners, MIRRI aims to support research and development in the field of biotechnology.
Services: Access to microorganisms/cell lines deposited in public collections / deposit of microorganisms/cell lines (public collection/patents) / phenotypic/molecular characterisation of microorganisms / identification/molecular typing of microorganisms / isolation/cultivation/preservation of microorganisms / microbial community analyses / microbial phylogenetic studies / screening/bioassays with / microorganisms / access to microbiological databases / consultancy/contract research / legal issues (e.g. Nagoya Protocol) / biosafety/biosecurity / training
Costs: Costs depend on the kind of service requested.
Access modes: Access modes depend on the kind of service requested.
Why MIRRI: MIRRI offers not only a broad spectrum of high quality microorganisms, but also a longlasting expertise in each field of microbiology. Aiming at harmonising the current microbial Biological Resource Centre (mBRC) landscape, MIRRI enables facilitated access to deposited microorganisms and is constantly improving the corresponding state-of-the-art service offers. Our experts ensure legal compliance of resources (Nagoya Protocol) and with the envisaged interoperability of existing and future databases researchers can exploit the full value of microorganisms.
Countries involved: Under development
Contact person: MIRRI Interim Secretariat
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Euro-BioImaging offers life scientists open access to imaging instruments, expertise, training opportunities, and data management services that they do not find at their home institutions or among their collaboration partners. All scientists, regardless of affiliation, area of expertise, or field of activity, can benefit from these pan-European open access services.
Services: Euro-BioImaging offers state-of-the-art imaging services through its internationally renowned facilities, called Nodes. Nodes cover the whole spectrum of biological and biomedical imaging, with an ever-growing portfolio of cutting-edge instruments. Researchers at any stage of their career can request access to over 45+ imaging technologies hosted at 33 Nodes located in 16 European countries and at EMBL. New technologies are included continuously to offer access to the most innovative and pioneering technologies on the market.
Costs: The access fees for each visit are individually discussed and agreed upon directly between the Euro-BioImaging user and the respective Euro-BioImaging Node as part of the pre-visit discussion during the project planning phase. The user is therefore fully informed of all costs that will arise related to the access to a Euro-BioImaging Node. The Euro-BioImaging Hub, taking care of all administrative work in Euro-BioImaging, do not charge any costs to the users! Access support for users is announced on the Euro-BioImaging Web Portal.
Access modes: Euro-BioImaging offers open access to its technology portfolio, which is put in place using a selection procedure based on scientific soundness and technical feasibility of the project. In most cases, scientists visit the requested Node to perform their experiments on-site, being supported throughout their project by expert technical staff. Access to the image data resources are remote, online and can be found via the Euro-BioImaging Web Portal.
Why Euro-BioImaging: All scientists, regardless of affiliation, area of expertise, or field of activity, can benefit from Euro-BioImaging’s pan-European open access services. For most technologies, scientists are invited to receive hands-on training at the imaging instrument of their choice so that they can generate the desired data sets themselves and expand their technological knowledge. Visits can vary in length between single days to several weeks or months, depending on the project’s need and individual circumstances. Scientists interested in accessing Euro BioImaging services simply submit a short description of their planned experiment via the online application portal. Senior scientists and Node staff will offer expert advice on the project’s scope and experimental set-up to ensure that the experiment has the best chance of success from the very first visit.
Countries involved: Austria, Bulgaria, Czech Republic, Denmark, Finland, France, Hungary, Israel, Italy , Norway, Poland, Portugal, Slovenia, Sweden, The Netherlands, United Kingdom, EMBL (intergovernmental organisation), Belgium (observer)
Contact person: Johanna Bischof, Alessandra Viale
The following RIs offer complementary services
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The European Marine Biological Research Centre (EMBRC-ERIC) is a Research Infrastructure including 29 Operators across 9 different European countries. EMBRC is dedicated for marine biology and ecology research. EMBRC offers to the scientific community, academic institutions and private companies a comprehensive set of services to study marine organisms and to give access to ecosystems. EMBRC is providing local or remote access to state-of-the-art national facilities such as renowned marine biological stations.
Services: Access to ecosystems / Marine biological resources (micro & macro, alive & fixed, wild & cultivated) / Experimental facilities / Technology platforms / E-Infrastructure, Data & services / Supporting facilities
Costs: Prices depend on the nature of the service and are available upon request.
Access modes: Through the 29 European operators, users can access the services remotely or on-site. The user has to select the service of interest, submit a proposal and he/she will receive feedback or be contacted.
Why EMBRC: Researchers should contact us in order to have access to marine ecosystems, marine biological resources and associated technological platforms for analysis.
Countries involved: BE, ES, FR, IT, GR, NO, PT, IL, UK
Contact person: info@embrc.eu
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EMPHASIS is a pan-European, distributed plant phenotyping infrastructure. EMPHASIS will focus on developing and enabling access to plant phenotyping infrastructure and provision of services essential for the analysis of crop performance with respect to structure, function, quality and interaction with the environment. It will thus support the exploitation of crop genetic diversity required for the enhancement of plant productivity and progress in plant breeding.
Services: In cooperation with EPPN2020, EMPHASIS offers access to plant phenotyping infrastructures, which includes high-throughput facilities / lean field facilities / intensive field facilities / assay development / data management
Costs: European-wide access to plant phenotyping infrastructures is currently under development in our partner project EPPN2020 and is provided via its homepage. Access will be accordingly provided by EMPHASIS once it reaches its operational phase.
Access modes: Through the 29 European operators, users can access the services remotely or on-site. The user has to select the service of interest, submit a proposal and he/she will receive feedback or be contacted.
Why EMPHASIS: EPPN2020 provides transnational access to plant phenotyping infrastructure as a basis for novel scientific approaches to quantitative plant assessment in high throughput. The installations represent a diverse set of facilities for plant phenotyping in Europe with focus on: i) non-invasive high-throughput phenotyping under controlled conditions, ii) destructive sampling aiming at assessing underlying traits helping to understand the genetic variability of different plant processes, iii) controlled field facilities allowing users to control rainfall and/or the concentration of air CO2 together with high-definition, non-invasive sensors. Transnational access will be available based on a simple and transparent access procedure.
Countries involved: Preparatory phase of the project: BE, FR, IT, NL, UK, DE
Contact person: Dr. Roland Pieruschka, Dr. Sven Fahrner
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ERINHA is a pan-European distributed life sciences research Infrastructure dedicated to the study of highly infectious emerging and re-emerging high-consequence pathogens (RG4 & unknown). It brings together leading European high containment and complementary research facilities and expertise required to perform cutting-edge research on highly infectious diseases. ERINHA provides access to its state of art BSL-4 laboratories and complementary capacities and expertise to perform excellence orientated in-vitro and in-vivo research projects, trainings and advise. A wide range of capabilities and functions from high basic research laboratory capacities to NHP modeling research are provided by ERINHA, as well as expertise of senior scientists and access to complementary functions (from BSL1 to BSL4, genomics, proteomics etc.). ERINHA produces the ideal environment to facilitate coordination of research on high-consequence pathogens in Europe. The infrastructure will contribute to the enhancement of the European and global capacity, capability and emergency preparedness in the response to global outbreaks. Since 2018, ERINHA has been granted landmark status by the European Strategy Forum on Research Infrastructures (ESFRI).
Services: Access to state of art European high containment (BSL4 & BSL3) and complementary facilities to advance research on high-consequence pathogens / In-vivo testing with a variety of animal models (including small rodents, ferrets, and non-human primates) / In-vitro experiments using highly pathogenic agents with both in-person and remote access possibilities. / Project coordination and management of large scale research programmes on high consequence pathogens / Training (General Biosecurity Training; Operations of a Biosafety Laboratory; Training for potential users) / Advice and scientific expertise provider (RG4 pathogens research, containment facilities construction, biosafety/biosecurity issues, sample transport etc.) / Access to pathogens specimens
Costs: For access costs information contact ERINHA Central Coordinating Unit (CCU) at contact@erinha.eu
Access modes: ERINHA provides in-person and remote access to its services. Projects can be submitted by academic, public and industrial users. For more information contact ERINHA CCU at contact@erinha.eu
Why ERINHA: The 2014-2015 Ebola outbreak and cases in Europe demonstrated the worldwide vulnerability and need for common action putting together rare high containment capacities and expertise to be able to increase European and global preparedness for outbreaks of high consequence pathogens. ERINHA facilitates access to required infrastructure capacities thanks to its CCU and multiple high containment and complementary European resources. It is a unique coordinated infrastrucuture providing transnational access to its facilities, large scope of services and shorter delays in access.
Countries involved: Austria (Medical University of Graz), Belgium (KUL), France (Inserm), Hungary (Ministry of Human Capacities), Netherlands (ERASMUS MC), Portugal (INSA), Spain (Instituto de Salud Carlos III), Sweden (FOHM)
Contact person: Diana Stepanyan-Yerdamian, Dylan Bonfils, contact@erinha.eu
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EU-OPENSCREEN integrates high-capacity screening platforms throughout Europe, which jointly use a rationally selected compound collection, comprising up to 140.000 commercial and proprietary compounds collected from European chemists. EU-OPENSCREEN offers to researchers from academic institutions, SMEs and industrial organisations open access to its shared resources. EU-OPENSCREEN will collaboratively develop novel molecular tool compounds with external users from various disciplines of the life sciences.
Services: High-throughput compound/ drug screening (HTS) / access to a unique European compound collection (> 100,000 compounds) / assay adaption / chemical optimization and profiling of preliminary ‘hits’ / bioprofiling of donated compounds / provision of standardised data / training and education activities
Costs: A screening project at a typical EU-OPENSCREEN screening site will cost 50-250k €, strongly depending on the number of screened substances and the maturity/ complexity of the assay. A compound replenishment fee structure applies to all projects using the EU-OPENSCREEN compound collection and users from countries which are members of the EU-OPENSCREEN ERIC will receive a discount on this cost.
Access modes: Users are requested to submit project proposal to the EU-OPENSCREEN office. Depending on the project requirements, the RI can be assessed remotely or on-site.
Why EU-OPENSCREEN: The majority of scientists in Europe do not have access to suitable technology platforms and compound collections, which are generally expensive to purchase, operate and maintain. As a large-scale research infrastructure (RI) with an ‘open’ pre-competitive character, EU-OPENSCREEN will cost-effectively overcome this limitation by: involving and providing access to Europe’s leading screening platforms and chemistry groups; offering a jointly used rationally designed compound collection; and operating an open-access bioactivity database which will be accessible on a global basis. EU-OPENSCREEN offers to support you through grant application processes and beyond for funding involving screening projects.
Countries involved: CZ, FI, DE, LV, NO, PO, ES, DK
Contact person: Project Manager: Dr. Tanja Miletic
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Instruct-ERIC is a pan-European research infrastructure in structural biology, making high-end technologies and methods available to scientists. Access is provided free for academic scientists at Instruct centres and includes expert support.
Services: Sample Preparation (Crystallisation, Nanobody Discovery, Protein Production) / Biomolecular Analysis (Imaging, Mass Spectrometry, Molecular Biophysics) / 3D Structural Analysis (Electron Microscopy, Magnetic Resonance Techniques, X-ray Techniques) / Compuational Services for Structural Biology (Bioinformatics Tools, Integrative Modelling, Crystallography, Electron Microscopy, NMR)
Costs: Free for academic users; on service-basis for commercial use (user access is on a fee for service basis; no obligation to disclose or publish data). Users can apply for travel and accommodation costs where a physical visit to an Instruct facility is required.
Access modes: Depending on the requested service, access can be on-site, remote, or mail-in sample.
Why Instruct-ERIC: Instruct is at the cutting edge of new technologies: automation, remote access, new detector methods, advanced imaging. Access to Instruct-ERIC infrastructure can help advance your research – more than 1200 peer-reviewed scientific publications acknowledge Instruct.
Countries involved: BE, CZ, EMBL, FI, FR, DE, GR, IL, IT, LV, LT, NL, PT, SK, SI, ES, UK
Contact person: Dr. Claudia Alen Amaro, Coordinator Head of Operations
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MIRRI is the pan-European research infrastructure for microbial resources [i.e. bacteria (including cyanobacteria), archaea, fungi, yeasts, plant viruses, bacteriophages and their isolated DNA]. In addition, the MIRRI repertoire also covers human, animal and plant cell cultures. By provision of high quality microorganisms, associated data and the broad expertise of our partners, MIRRI aims to support research and development in the field of biotechnology.
Services: Access to microorganisms/cell lines deposited in public collections / deposit of microorganisms/cell lines (public collection/patents) / phenotypic/molecular characterisation of microorganisms / identification/molecular typing of microorganisms / isolation/cultivation/preservation of microorganisms / microbial community analyses / microbial phylogenetic studies / screening/bioassays with / microorganisms / access to microbiological databases / consultancy/contract research / legal issues (e.g. Nagoya Protocol) / biosafety/biosecurity / training
Costs: Costs depend on the kind of service requested.
Access modes: Access modes depend on the kind of service requested.
Why MIRRI: MIRRI offers not only a broad spectrum of high quality microorganisms, but also a longlasting expertise in each field of microbiology. Aiming at harmonising the current microbial Biological Resource Centre (mBRC) landscape, MIRRI enables facilitated access to deposited microorganisms and is constantly improving the corresponding state-of-the-art service offers. Our experts ensure legal compliance of resources (Nagoya Protocol) and with the envisaged interoperability of existing and future databases researchers can exploit the full value of microorganisms.
Countries involved: Under development
Contact person: MIRRI Interim Secretariat
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Euro-BioImaging offers life scientists open access to imaging instruments, expertise, training opportunities, and data management services that they do not find at their home institutions or among their collaboration partners. All scientists, regardless of affiliation, area of expertise, or field of activity, can benefit from these pan-European open access services.
Services: Euro-BioImaging offers state-of-the-art imaging services through its internationally renowned facilities, called Nodes. Nodes cover the whole spectrum of biological and biomedical imaging, with an ever-growing portfolio of cutting-edge instruments. Researchers at any stage of their career can request access to over 45+ imaging technologies hosted at 33 Nodes located in 16 European countries and at EMBL. New technologies are included continuously to offer access to the most innovative and pioneering technologies on the market.
Costs: The access fees for each visit are individually discussed and agreed upon directly between the Euro-BioImaging user and the respective Euro-BioImaging Node as part of the pre-visit discussion during the project planning phase. The user is therefore fully informed of all costs that will arise related to the access to a Euro-BioImaging Node. The Euro-BioImaging Hub, taking care of all administrative work in Euro-BioImaging, do not charge any costs to the users! Access support for users is announced on the Euro-BioImaging Web Portal.
Access modes: Euro-BioImaging offers open access to its technology portfolio, which is put in place using a selection procedure based on scientific soundness and technical feasibility of the project. In most cases, scientists visit the requested Node to perform their experiments on-site, being supported throughout their project by expert technical staff. Access to the image data resources are remote, online and can be found via the Euro-BioImaging Web Portal.
Why Euro-BioImaging: All scientists, regardless of affiliation, area of expertise, or field of activity, can benefit from Euro-BioImaging’s pan-European open access services. For most technologies, scientists are invited to receive hands-on training at the imaging instrument of their choice so that they can generate the desired data sets themselves and expand their technological knowledge. Visits can vary in length between single days to several weeks or months, depending on the project’s need and individual circumstances. Scientists interested in accessing Euro BioImaging services simply submit a short description of their planned experiment via the online application portal. Senior scientists and Node staff will offer expert advice on the project’s scope and experimental set-up to ensure that the experiment has the best chance of success from the very first visit.
Countries involved: Austria, Bulgaria, Czech Republic, Denmark, Finland, France, Hungary, Israel, Italy , Norway, Poland, Portugal, Slovenia, Sweden, The Netherlands, United Kingdom, EMBL (intergovernmental organisation), Belgium (observer)
Contact person: Johanna Bischof, Alessandra Viale
The following RIs offer complementary services
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EATRIS is the European infrastructure for translational medicine. The infrastructure brings together resources and services for research communities to translate scientific discoveries into benefits for patients.
Services: Support funding applications (Identification of partners for consortium building, assessment of the project plan’s impact and innovation potential) / Translational research facilities and expertise for development of novel biomarkers, diagnostics and therapeutics / Molecular, functional & hybrid imaging technologies, preclinical models, samples, patient cohorts, GMP manufacturing / Regulatory and Health Technology Assessment (HTA) expertise / Advice on intellectual property issues and industry partnering strategy (innovation management)
Costs: Costs are calculated on a case by case basis depending on the service required; some services can also be provided as part of funding proposals with EATRIS joining consortia as partner or subcontractor.
Access modes: Services performed can be offered either centrally by the coordination and support team based in Amsterdam or remotely by the EATRIS institutions.
Why EATRIS: Translating novel biology insights into effective interventions or medical applications is a highly complex process. It requires significant dedicated expertise, facilities and resources. We believe in your medical innovation and we want to support you by bringing together the multi-disciplinary expertise and infrastructure required for optimising your translational trajectory. Working with EATRIS gives greater confidence in the translational feasibility of your project and its impact.
Countries involved: FR, NL, CZ, HR, SE, NO, FI, IT, ES, SI, LU, LV, PO, BG
Contact person: Florence Bietrix
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MIRRI is the pan-European research infrastructure for microbial resources [i.e. bacteria (including cyanobacteria), archaea, fungi, yeasts, plant viruses, bacteriophages and their isolated DNA]. In addition, the MIRRI repertoire also covers human, animal and plant cell cultures. By provision of high quality microorganisms, associated data and the broad expertise of our partners, MIRRI aims to support research and development in the field of biotechnology.
Services: Access to microorganisms/cell lines deposited in public collections / deposit of microorganisms/cell lines (public collection/patents) / phenotypic/molecular characterisation of microorganisms / identification/molecular typing of microorganisms / isolation/cultivation/preservation of microorganisms / microbial community analyses / microbial phylogenetic studies / screening/bioassays with / microorganisms / access to microbiological databases / consultancy/contract research / legal issues (e.g. Nagoya Protocol) / biosafety/biosecurity / training
Costs: Costs depend on the kind of service requested.
Access modes: Access modes depend on the kind of service requested.
Why MIRRI: MIRRI offers not only a broad spectrum of high quality microorganisms, but also a longlasting expertise in each field of microbiology. Aiming at harmonising the current microbial Biological Resource Centre (mBRC) landscape, MIRRI enables facilitated access to deposited microorganisms and is constantly improving the corresponding state-of-the-art service offers. Our experts ensure legal compliance of resources (Nagoya Protocol) and with the envisaged interoperability of existing and future databases researchers can exploit the full value of microorganisms.
Countries involved: Under development
Contact person: MIRRI Interim Secretariat
The following RIs offer complementary services
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The European Marine Biological Research Centre (EMBRC-ERIC) is a Research Infrastructure including 29 Operators across 9 different European countries. EMBRC is dedicated for marine biology and ecology research. EMBRC offers to the scientific community, academic institutions and private companies a comprehensive set of services to study marine organisms and to give access to ecosystems. EMBRC is providing local or remote access to state-of-the-art national facilities such as renowned marine biological stations.
Services: Access to ecosystems / Marine biological resources (micro & macro, alive & fixed, wild & cultivated) / Experimental facilities / Technology platforms / E-Infrastructure, Data & services / Supporting facilities
Costs: Prices depend on the nature of the service and are available upon request.
Access modes: Through the 29 European operators, users can access the services remotely or on-site. The user has to select the service of interest, submit a proposal and he/she will receive feedback or be contacted.
Why EMBRC: Researchers should contact us in order to have access to marine ecosystems, marine biological resources and associated technological platforms for analysis.
Countries involved: BE, ES, FR, IT, GR, NO, PT, IL, UK
Contact person: info@embrc.eu
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ERINHA is a pan-European distributed life sciences research Infrastructure dedicated to the study of highly infectious emerging and re-emerging high-consequence pathogens (RG4 & unknown). It brings together leading European high containment and complementary research facilities and expertise required to perform cutting-edge research on highly infectious diseases. ERINHA provides access to its state of art BSL-4 laboratories and complementary capacities and expertise to perform excellence orientated in-vitro and in-vivo research projects, trainings and advise. A wide range of capabilities and functions from high basic research laboratory capacities to NHP modeling research are provided by ERINHA, as well as expertise of senior scientists and access to complementary functions (from BSL1 to BSL4, genomics, proteomics etc.). ERINHA produces the ideal environment to facilitate coordination of research on high-consequence pathogens in Europe. The infrastructure will contribute to the enhancement of the European and global capacity, capability and emergency preparedness in the response to global outbreaks. Since 2018, ERINHA has been granted landmark status by the European Strategy Forum on Research Infrastructures (ESFRI).
Services: Access to state of art European high containment (BSL4 & BSL3) and complementary facilities to advance research on high-consequence pathogens / In-vivo testing with a variety of animal models (including small rodents, ferrets, and non-human primates) / In-vitro experiments using highly pathogenic agents with both in-person and remote access possibilities. / Project coordination and management of large scale research programmes on high consequence pathogens / Training (General Biosecurity Training; Operations of a Biosafety Laboratory; Training for potential users) / Advice and scientific expertise provider (RG4 pathogens research, containment facilities construction, biosafety/biosecurity issues, sample transport etc.) / Access to pathogens specimens
Costs: For access costs information contact ERINHA Central Coordinating Unit (CCU) at contact@erinha.eu
Access modes: ERINHA provides in-person and remote access to its services. Projects can be submitted by academic, public and industrial users. For more information contact ERINHA CCU at contact@erinha.eu
Why ERINHA: The 2014-2015 Ebola outbreak and cases in Europe demonstrated the worldwide vulnerability and need for common action putting together rare high containment capacities and expertise to be able to increase European and global preparedness for outbreaks of high consequence pathogens. ERINHA facilitates access to required infrastructure capacities thanks to its CCU and multiple high containment and complementary European resources. It is a unique coordinated infrastrucuture providing transnational access to its facilities, large scope of services and shorter delays in access.
Countries involved: Austria (Medical University of Graz), Belgium (KUL), France (Inserm), Hungary (Ministry of Human Capacities), Netherlands (ERASMUS MC), Portugal (INSA), Spain (Instituto de Salud Carlos III), Sweden (FOHM)
Contact person: Diana Stepanyan-Yerdamian, Dylan Bonfils, contact@erinha.eu
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EATRIS is the European infrastructure for translational medicine. The infrastructure brings together resources and services for research communities to translate scientific discoveries into benefits for patients.
Services: Support funding applications (Identification of partners for consortium building, assessment of the project plan’s impact and innovation potential) / Translational research facilities and expertise for development of novel biomarkers, diagnostics and therapeutics / Molecular, functional & hybrid imaging technologies, preclinical models, samples, patient cohorts, GMP manufacturing / Regulatory and Health Technology Assessment (HTA) expertise / Advice on intellectual property issues and industry partnering strategy (innovation management)
Costs: Costs are calculated on a case by case basis depending on the service required; some services can also be provided as part of funding proposals with EATRIS joining consortia as partner or subcontractor.
Access modes: Services performed can be offered either centrally by the coordination and support team based in Amsterdam or remotely by the EATRIS institutions.
Why EATRIS: Translating novel biology insights into effective interventions or medical applications is a highly complex process. It requires significant dedicated expertise, facilities and resources. We believe in your medical innovation and we want to support you by bringing together the multi-disciplinary expertise and infrastructure required for optimising your translational trajectory. Working with EATRIS gives greater confidence in the translational feasibility of your project and its impact.
Countries involved: FR, NL, CZ, HR, SE, NO, FI, IT, ES, SI, LU, LV, PO, BG
Contact person: Florence Bietrix
The following RIs offer complementary services
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EMPHASIS is a pan-European, distributed plant phenotyping infrastructure. EMPHASIS will focus on developing and enabling access to plant phenotyping infrastructure and provision of services essential for the analysis of crop performance with respect to structure, function, quality and interaction with the environment. It will thus support the exploitation of crop genetic diversity required for the enhancement of plant productivity and progress in plant breeding.
Services: In cooperation with EPPN2020, EMPHASIS offers access to plant phenotyping infrastructures, which includes high-throughput facilities / lean field facilities / intensive field facilities / assay development / data management
Costs: European-wide access to plant phenotyping infrastructures is currently under development in our partner project EPPN2020 and is provided via its homepage. Access will be accordingly provided by EMPHASIS once it reaches its operational phase.
Access modes: Through the 29 European operators, users can access the services remotely or on-site. The user has to select the service of interest, submit a proposal and he/she will receive feedback or be contacted.
Why EMPHASIS: EPPN2020 provides transnational access to plant phenotyping infrastructure as a basis for novel scientific approaches to quantitative plant assessment in high throughput. The installations represent a diverse set of facilities for plant phenotyping in Europe with focus on: i) non-invasive high-throughput phenotyping under controlled conditions, ii) destructive sampling aiming at assessing underlying traits helping to understand the genetic variability of different plant processes, iii) controlled field facilities allowing users to control rainfall and/or the concentration of air CO2 together with high-definition, non-invasive sensors. Transnational access will be available based on a simple and transparent access procedure.
Countries involved: Preparatory phase of the project: BE, FR, IT, NL, UK, DE
Contact person: Dr. Roland Pieruschka, Dr. Sven Fahrner
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EMPHASIS is a pan-European, distributed plant phenotyping infrastructure. EMPHASIS will focus on developing and enabling access to plant phenotyping infrastructure and provision of services essential for the analysis of crop performance with respect to structure, function, quality and interaction with the environment. It will thus support the exploitation of crop genetic diversity required for the enhancement of plant productivity and progress in plant breeding.
Services: In cooperation with EPPN2020, EMPHASIS offers access to plant phenotyping infrastructures, which includes high-throughput facilities / lean field facilities / intensive field facilities / assay development / data management
Costs: European-wide access to plant phenotyping infrastructures is currently under development in our partner project EPPN2020 and is provided via its homepage. Access will be accordingly provided by EMPHASIS once it reaches its operational phase.
Access modes: Through the 29 European operators, users can access the services remotely or on-site. The user has to select the service of interest, submit a proposal and he/she will receive feedback or be contacted.
Why EMPHASIS: EPPN2020 provides transnational access to plant phenotyping infrastructure as a basis for novel scientific approaches to quantitative plant assessment in high throughput. The installations represent a diverse set of facilities for plant phenotyping in Europe with focus on: i) non-invasive high-throughput phenotyping under controlled conditions, ii) destructive sampling aiming at assessing underlying traits helping to understand the genetic variability of different plant processes, iii) controlled field facilities allowing users to control rainfall and/or the concentration of air CO2 together with high-definition, non-invasive sensors. Transnational access will be available based on a simple and transparent access procedure.
Countries involved: Preparatory phase of the project: BE, FR, IT, NL, UK, DE
Contact person: Dr. Roland Pieruschka, Dr. Sven Fahrner
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Instruct-ERIC is a pan-European research infrastructure in structural biology, making high-end technologies and methods available to scientists. Access is provided free for academic scientists at Instruct centres and includes expert support.
Services: Sample Preparation (Crystallisation, Nanobody Discovery, Protein Production) / Biomolecular Analysis (Imaging, Mass Spectrometry, Molecular Biophysics) / 3D Structural Analysis (Electron Microscopy, Magnetic Resonance Techniques, X-ray Techniques) / Compuational Services for Structural Biology (Bioinformatics Tools, Integrative Modelling, Crystallography, Electron Microscopy, NMR)
Costs: Free for academic users; on service-basis for commercial use (user access is on a fee for service basis; no obligation to disclose or publish data). Users can apply for travel and accommodation costs where a physical visit to an Instruct facility is required.
Access modes: Depending on the requested service, access can be on-site, remote, or mail-in sample.
Why Instruct-ERIC: Instruct is at the cutting edge of new technologies: automation, remote access, new detector methods, advanced imaging. Access to Instruct-ERIC infrastructure can help advance your research – more than 1200 peer-reviewed scientific publications acknowledge Instruct.
Countries involved: BE, CZ, EMBL, FI, FR, DE, GR, IL, IT, LV, LT, NL, PT, SK, SI, ES, UK
Contact person: Dr. Claudia Alen Amaro, Coordinator Head of Operations
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Instruct-ERIC is a pan-European research infrastructure in structural biology, making high-end technologies and methods available to scientists. Access is provided free for academic scientists at Instruct centres and includes expert support.
Services: Sample Preparation (Crystallisation, Nanobody Discovery, Protein Production) / Biomolecular Analysis (Imaging, Mass Spectrometry, Molecular Biophysics) / 3D Structural Analysis (Electron Microscopy, Magnetic Resonance Techniques, X-ray Techniques) / Compuational Services for Structural Biology (Bioinformatics Tools, Integrative Modelling, Crystallography, Electron Microscopy, NMR)
Costs: Free for academic users; on service-basis for commercial use (user access is on a fee for service basis; no obligation to disclose or publish data). Users can apply for travel and accommodation costs where a physical visit to an Instruct facility is required.
Access modes: Depending on the requested service, access can be on-site, remote, or mail-in sample.
Why Instruct-ERIC: Instruct is at the cutting edge of new technologies: automation, remote access, new detector methods, advanced imaging. Access to Instruct-ERIC infrastructure can help advance your research – more than 1200 peer-reviewed scientific publications acknowledge Instruct.
Countries involved: BE, CZ, EMBL, FI, FR, DE, GR, IL, IT, LV, LT, NL, PT, SK, SI, ES, UK
Contact person: Dr. Claudia Alen Amaro, Coordinator Head of Operations
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EMPHASIS is a pan-European, distributed plant phenotyping infrastructure. EMPHASIS will focus on developing and enabling access to plant phenotyping infrastructure and provision of services essential for the analysis of crop performance with respect to structure, function, quality and interaction with the environment. It will thus support the exploitation of crop genetic diversity required for the enhancement of plant productivity and progress in plant breeding.
Services: In cooperation with EPPN2020, EMPHASIS offers access to plant phenotyping infrastructures, which includes high-throughput facilities / lean field facilities / intensive field facilities / assay development / data management
Costs: European-wide access to plant phenotyping infrastructures is currently under development in our partner project EPPN2020 and is provided via its homepage. Access will be accordingly provided by EMPHASIS once it reaches its operational phase.
Access modes: Through the 29 European operators, users can access the services remotely or on-site. The user has to select the service of interest, submit a proposal and he/she will receive feedback or be contacted.
Why EMPHASIS: EPPN2020 provides transnational access to plant phenotyping infrastructure as a basis for novel scientific approaches to quantitative plant assessment in high throughput. The installations represent a diverse set of facilities for plant phenotyping in Europe with focus on: i) non-invasive high-throughput phenotyping under controlled conditions, ii) destructive sampling aiming at assessing underlying traits helping to understand the genetic variability of different plant processes, iii) controlled field facilities allowing users to control rainfall and/or the concentration of air CO2 together with high-definition, non-invasive sensors. Transnational access will be available based on a simple and transparent access procedure.
Countries involved: Preparatory phase of the project: BE, FR, IT, NL, UK, DE
Contact person: Dr. Roland Pieruschka, Dr. Sven Fahrner
-
ERINHA is a pan-European distributed life sciences research Infrastructure dedicated to the study of highly infectious emerging and re-emerging high-consequence pathogens (RG4 & unknown). It brings together leading European high containment and complementary research facilities and expertise required to perform cutting-edge research on highly infectious diseases. ERINHA provides access to its state of art BSL-4 laboratories and complementary capacities and expertise to perform excellence orientated in-vitro and in-vivo research projects, trainings and advise. A wide range of capabilities and functions from high basic research laboratory capacities to NHP modeling research are provided by ERINHA, as well as expertise of senior scientists and access to complementary functions (from BSL1 to BSL4, genomics, proteomics etc.). ERINHA produces the ideal environment to facilitate coordination of research on high-consequence pathogens in Europe. The infrastructure will contribute to the enhancement of the European and global capacity, capability and emergency preparedness in the response to global outbreaks. Since 2018, ERINHA has been granted landmark status by the European Strategy Forum on Research Infrastructures (ESFRI).
Services: Access to state of art European high containment (BSL4 & BSL3) and complementary facilities to advance research on high-consequence pathogens / In-vivo testing with a variety of animal models (including small rodents, ferrets, and non-human primates) / In-vitro experiments using highly pathogenic agents with both in-person and remote access possibilities. / Project coordination and management of large scale research programmes on high consequence pathogens / Training (General Biosecurity Training; Operations of a Biosafety Laboratory; Training for potential users) / Advice and scientific expertise provider (RG4 pathogens research, containment facilities construction, biosafety/biosecurity issues, sample transport etc.) / Access to pathogens specimens
Costs: For access costs information contact ERINHA Central Coordinating Unit (CCU) at contact@erinha.eu
Access modes: ERINHA provides in-person and remote access to its services. Projects can be submitted by academic, public and industrial users. For more information contact ERINHA CCU at contact@erinha.eu
Why ERINHA: The 2014-2015 Ebola outbreak and cases in Europe demonstrated the worldwide vulnerability and need for common action putting together rare high containment capacities and expertise to be able to increase European and global preparedness for outbreaks of high consequence pathogens. ERINHA facilitates access to required infrastructure capacities thanks to its CCU and multiple high containment and complementary European resources. It is a unique coordinated infrastrucuture providing transnational access to its facilities, large scope of services and shorter delays in access.
Countries involved: Austria (Medical University of Graz), Belgium (KUL), France (Inserm), Hungary (Ministry of Human Capacities), Netherlands (ERASMUS MC), Portugal (INSA), Spain (Instituto de Salud Carlos III), Sweden (FOHM)
Contact person: Diana Stepanyan-Yerdamian, Dylan Bonfils, contact@erinha.eu
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The European Marine Biological Research Centre (EMBRC-ERIC) is a Research Infrastructure including 29 Operators across 9 different European countries. EMBRC is dedicated for marine biology and ecology research. EMBRC offers to the scientific community, academic institutions and private companies a comprehensive set of services to study marine organisms and to give access to ecosystems. EMBRC is providing local or remote access to state-of-the-art national facilities such as renowned marine biological stations.
Services: Access to ecosystems / Marine biological resources (micro & macro, alive & fixed, wild & cultivated) / Experimental facilities / Technology platforms / E-Infrastructure, Data & services / Supporting facilities
Costs: Prices depend on the nature of the service and are available upon request.
Access modes: Through the 29 European operators, users can access the services remotely or on-site. The user has to select the service of interest, submit a proposal and he/she will receive feedback or be contacted.
Why EMBRC: Researchers should contact us in order to have access to marine ecosystems, marine biological resources and associated technological platforms for analysis.
Countries involved: BE, ES, FR, IT, GR, NO, PT, IL, UK
Contact person: info@embrc.eu
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EATRIS is the European infrastructure for translational medicine. The infrastructure brings together resources and services for research communities to translate scientific discoveries into benefits for patients.
Services: Support funding applications (Identification of partners for consortium building, assessment of the project plan’s impact and innovation potential) / Translational research facilities and expertise for development of novel biomarkers, diagnostics and therapeutics / Molecular, functional & hybrid imaging technologies, preclinical models, samples, patient cohorts, GMP manufacturing / Regulatory and Health Technology Assessment (HTA) expertise / Advice on intellectual property issues and industry partnering strategy (innovation management)
Costs: Costs are calculated on a case by case basis depending on the service required; some services can also be provided as part of funding proposals with EATRIS joining consortia as partner or subcontractor.
Access modes: Services performed can be offered either centrally by the coordination and support team based in Amsterdam or remotely by the EATRIS institutions.
Why EATRIS: Translating novel biology insights into effective interventions or medical applications is a highly complex process. It requires significant dedicated expertise, facilities and resources. We believe in your medical innovation and we want to support you by bringing together the multi-disciplinary expertise and infrastructure required for optimising your translational trajectory. Working with EATRIS gives greater confidence in the translational feasibility of your project and its impact.
Countries involved: FR, NL, CZ, HR, SE, NO, FI, IT, ES, SI, LU, LV, PO, BG
Contact person: Florence Bietrix
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INFRAFRONTIER is the European research infrastructure for the development, phenotyping, archiving and distribution of model mammalian genomes. It is formed by more than 25 research centres in 14 European countries and Canada. In INFRAFRONTIER these partners join forces to commonly advance the basic understanding of human health and disease using mouse and rodent models.
Services: Archiving and distribution of scientifically valuable mutant mouse strains / Rodent model development (mouse and rat) using gene targeting in embryonic ES-cells or CRISPR/CAS9 technologies/ Systemic phenotyping of mutant mice for a whole-organism view on gene function / Germ-free (axenic) mice/ Validated genetically engineered mouse models of cancer / Access to comprehensinve expertise and training
Costs: Some of the INFRAFRONTIER resources and services are provided free of charge, others entail user fees to recover costs. There are periodic Open Calls to fund researchers, for detailed information see the INFRAFRONTIER website.
Access modes: Access modalities vary with the kind of resource or service requested.
Why INFRAFRONTIER: INFRAFRONTIER provides access to unique resources and expertise to advance the understanding of human health and disease using mammalian models. Our users can rely on highest quality standards and long-standing experience. INFRAFRONTIER’s one-stop-shop facilitates efficient research.
Countries involved: DE, GR, FI, CZ, FR, EMBL
Contact person: INFRAFRONTIER Scientific User Support
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EATRIS is the European infrastructure for translational medicine. The infrastructure brings together resources and services for research communities to translate scientific discoveries into benefits for patients.
Services: Support funding applications (Identification of partners for consortium building, assessment of the project plan’s impact and innovation potential) / Translational research facilities and expertise for development of novel biomarkers, diagnostics and therapeutics / Molecular, functional & hybrid imaging technologies, preclinical models, samples, patient cohorts, GMP manufacturing / Regulatory and Health Technology Assessment (HTA) expertise / Advice on intellectual property issues and industry partnering strategy (innovation management)
Costs: Costs are calculated on a case by case basis depending on the service required; some services can also be provided as part of funding proposals with EATRIS joining consortia as partner or subcontractor.
Access modes: Services performed can be offered either centrally by the coordination and support team based in Amsterdam or remotely by the EATRIS institutions.
Why EATRIS: Translating novel biology insights into effective interventions or medical applications is a highly complex process. It requires significant dedicated expertise, facilities and resources. We believe in your medical innovation and we want to support you by bringing together the multi-disciplinary expertise and infrastructure required for optimising your translational trajectory. Working with EATRIS gives greater confidence in the translational feasibility of your project and its impact.
Countries involved: FR, NL, CZ, HR, SE, NO, FI, IT, ES, SI, LU, LV, PO, BG
Contact person: Florence Bietrix
The following RIs offer complementary services
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ERINHA is a pan-European distributed life sciences research Infrastructure dedicated to the study of highly infectious emerging and re-emerging high-consequence pathogens (RG4 & unknown). It brings together leading European high containment and complementary research facilities and expertise required to perform cutting-edge research on highly infectious diseases. ERINHA provides access to its state of art BSL-4 laboratories and complementary capacities and expertise to perform excellence orientated in-vitro and in-vivo research projects, trainings and advise. A wide range of capabilities and functions from high basic research laboratory capacities to NHP modeling research are provided by ERINHA, as well as expertise of senior scientists and access to complementary functions (from BSL1 to BSL4, genomics, proteomics etc.). ERINHA produces the ideal environment to facilitate coordination of research on high-consequence pathogens in Europe. The infrastructure will contribute to the enhancement of the European and global capacity, capability and emergency preparedness in the response to global outbreaks. Since 2018, ERINHA has been granted landmark status by the European Strategy Forum on Research Infrastructures (ESFRI).
Services: Access to state of art European high containment (BSL4 & BSL3) and complementary facilities to advance research on high-consequence pathogens / In-vivo testing with a variety of animal models (including small rodents, ferrets, and non-human primates) / In-vitro experiments using highly pathogenic agents with both in-person and remote access possibilities. / Project coordination and management of large scale research programmes on high consequence pathogens / Training (General Biosecurity Training; Operations of a Biosafety Laboratory; Training for potential users) / Advice and scientific expertise provider (RG4 pathogens research, containment facilities construction, biosafety/biosecurity issues, sample transport etc.) / Access to pathogens specimens
Costs: For access costs information contact ERINHA Central Coordinating Unit (CCU) at contact@erinha.eu
Access modes: ERINHA provides in-person and remote access to its services. Projects can be submitted by academic, public and industrial users. For more information contact ERINHA CCU at contact@erinha.eu
Why ERINHA: The 2014-2015 Ebola outbreak and cases in Europe demonstrated the worldwide vulnerability and need for common action putting together rare high containment capacities and expertise to be able to increase European and global preparedness for outbreaks of high consequence pathogens. ERINHA facilitates access to required infrastructure capacities thanks to its CCU and multiple high containment and complementary European resources. It is a unique coordinated infrastrucuture providing transnational access to its facilities, large scope of services and shorter delays in access.
Countries involved: Austria (Medical University of Graz), Belgium (KUL), France (Inserm), Hungary (Ministry of Human Capacities), Netherlands (ERASMUS MC), Portugal (INSA), Spain (Instituto de Salud Carlos III), Sweden (FOHM)
Contact person: Diana Stepanyan-Yerdamian, Dylan Bonfils, contact@erinha.eu
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EU-OPENSCREEN integrates high-capacity screening platforms throughout Europe, which jointly use a rationally selected compound collection, comprising up to 140.000 commercial and proprietary compounds collected from European chemists. EU-OPENSCREEN offers to researchers from academic institutions, SMEs and industrial organisations open access to its shared resources. EU-OPENSCREEN will collaboratively develop novel molecular tool compounds with external users from various disciplines of the life sciences.
Services: High-throughput compound/ drug screening (HTS) / access to a unique European compound collection (> 100,000 compounds) / assay adaption / chemical optimization and profiling of preliminary ‘hits’ / bioprofiling of donated compounds / provision of standardised data / training and education activities
Costs: A screening project at a typical EU-OPENSCREEN screening site will cost 50-250k €, strongly depending on the number of screened substances and the maturity/ complexity of the assay. A compound replenishment fee structure applies to all projects using the EU-OPENSCREEN compound collection and users from countries which are members of the EU-OPENSCREEN ERIC will receive a discount on this cost.
Access modes: Users are requested to submit project proposal to the EU-OPENSCREEN office. Depending on the project requirements, the RI can be assessed remotely or on-site.
Why EU-OPENSCREEN: The majority of scientists in Europe do not have access to suitable technology platforms and compound collections, which are generally expensive to purchase, operate and maintain. As a large-scale research infrastructure (RI) with an ‘open’ pre-competitive character, EU-OPENSCREEN will cost-effectively overcome this limitation by: involving and providing access to Europe’s leading screening platforms and chemistry groups; offering a jointly used rationally designed compound collection; and operating an open-access bioactivity database which will be accessible on a global basis. EU-OPENSCREEN offers to support you through grant application processes and beyond for funding involving screening projects.
Countries involved: CZ, FI, DE, LV, NO, PO, ES, DK
Contact person: Project Manager: Dr. Tanja Miletic
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EATRIS is the European infrastructure for translational medicine. The infrastructure brings together resources and services for research communities to translate scientific discoveries into benefits for patients.
Services: Support funding applications (Identification of partners for consortium building, assessment of the project plan’s impact and innovation potential) / Translational research facilities and expertise for development of novel biomarkers, diagnostics and therapeutics / Molecular, functional & hybrid imaging technologies, preclinical models, samples, patient cohorts, GMP manufacturing / Regulatory and Health Technology Assessment (HTA) expertise / Advice on intellectual property issues and industry partnering strategy (innovation management)
Costs: Costs are calculated on a case by case basis depending on the service required; some services can also be provided as part of funding proposals with EATRIS joining consortia as partner or subcontractor.
Access modes: Services performed can be offered either centrally by the coordination and support team based in Amsterdam or remotely by the EATRIS institutions.
Why EATRIS: Translating novel biology insights into effective interventions or medical applications is a highly complex process. It requires significant dedicated expertise, facilities and resources. We believe in your medical innovation and we want to support you by bringing together the multi-disciplinary expertise and infrastructure required for optimising your translational trajectory. Working with EATRIS gives greater confidence in the translational feasibility of your project and its impact.
Countries involved: FR, NL, CZ, HR, SE, NO, FI, IT, ES, SI, LU, LV, PO, BG
Contact person: Florence Bietrix
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EMPHASIS is a pan-European, distributed plant phenotyping infrastructure. EMPHASIS will focus on developing and enabling access to plant phenotyping infrastructure and provision of services essential for the analysis of crop performance with respect to structure, function, quality and interaction with the environment. It will thus support the exploitation of crop genetic diversity required for the enhancement of plant productivity and progress in plant breeding.
Services: In cooperation with EPPN2020, EMPHASIS offers access to plant phenotyping infrastructures, which includes high-throughput facilities / lean field facilities / intensive field facilities / assay development / data management
Costs: European-wide access to plant phenotyping infrastructures is currently under development in our partner project EPPN2020 and is provided via its homepage. Access will be accordingly provided by EMPHASIS once it reaches its operational phase.
Access modes: Through the 29 European operators, users can access the services remotely or on-site. The user has to select the service of interest, submit a proposal and he/she will receive feedback or be contacted.
Why EMPHASIS: EPPN2020 provides transnational access to plant phenotyping infrastructure as a basis for novel scientific approaches to quantitative plant assessment in high throughput. The installations represent a diverse set of facilities for plant phenotyping in Europe with focus on: i) non-invasive high-throughput phenotyping under controlled conditions, ii) destructive sampling aiming at assessing underlying traits helping to understand the genetic variability of different plant processes, iii) controlled field facilities allowing users to control rainfall and/or the concentration of air CO2 together with high-definition, non-invasive sensors. Transnational access will be available based on a simple and transparent access procedure.
Countries involved: Preparatory phase of the project: BE, FR, IT, NL, UK, DE
Contact person: Dr. Roland Pieruschka, Dr. Sven Fahrner
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ERINHA is a pan-European distributed life sciences research Infrastructure dedicated to the study of highly infectious emerging and re-emerging high-consequence pathogens (RG4 & unknown). It brings together leading European high containment and complementary research facilities and expertise required to perform cutting-edge research on highly infectious diseases. ERINHA provides access to its state of art BSL-4 laboratories and complementary capacities and expertise to perform excellence orientated in-vitro and in-vivo research projects, trainings and advise. A wide range of capabilities and functions from high basic research laboratory capacities to NHP modeling research are provided by ERINHA, as well as expertise of senior scientists and access to complementary functions (from BSL1 to BSL4, genomics, proteomics etc.). ERINHA produces the ideal environment to facilitate coordination of research on high-consequence pathogens in Europe. The infrastructure will contribute to the enhancement of the European and global capacity, capability and emergency preparedness in the response to global outbreaks. Since 2018, ERINHA has been granted landmark status by the European Strategy Forum on Research Infrastructures (ESFRI).
Services: Access to state of art European high containment (BSL4 & BSL3) and complementary facilities to advance research on high-consequence pathogens / In-vivo testing with a variety of animal models (including small rodents, ferrets, and non-human primates) / In-vitro experiments using highly pathogenic agents with both in-person and remote access possibilities. / Project coordination and management of large scale research programmes on high consequence pathogens / Training (General Biosecurity Training; Operations of a Biosafety Laboratory; Training for potential users) / Advice and scientific expertise provider (RG4 pathogens research, containment facilities construction, biosafety/biosecurity issues, sample transport etc.) / Access to pathogens specimens
Costs: For access costs information contact ERINHA Central Coordinating Unit (CCU) at contact@erinha.eu
Access modes: ERINHA provides in-person and remote access to its services. Projects can be submitted by academic, public and industrial users. For more information contact ERINHA CCU at contact@erinha.eu
Why ERINHA: The 2014-2015 Ebola outbreak and cases in Europe demonstrated the worldwide vulnerability and need for common action putting together rare high containment capacities and expertise to be able to increase European and global preparedness for outbreaks of high consequence pathogens. ERINHA facilitates access to required infrastructure capacities thanks to its CCU and multiple high containment and complementary European resources. It is a unique coordinated infrastrucuture providing transnational access to its facilities, large scope of services and shorter delays in access.
Countries involved: Austria (Medical University of Graz), Belgium (KUL), France (Inserm), Hungary (Ministry of Human Capacities), Netherlands (ERASMUS MC), Portugal (INSA), Spain (Instituto de Salud Carlos III), Sweden (FOHM)
Contact person: Diana Stepanyan-Yerdamian, Dylan Bonfils, contact@erinha.eu
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MIRRI is the pan-European research infrastructure for microbial resources [i.e. bacteria (including cyanobacteria), archaea, fungi, yeasts, plant viruses, bacteriophages and their isolated DNA]. In addition, the MIRRI repertoire also covers human, animal and plant cell cultures. By provision of high quality microorganisms, associated data and the broad expertise of our partners, MIRRI aims to support research and development in the field of biotechnology.
Services: Access to microorganisms/cell lines deposited in public collections / deposit of microorganisms/cell lines (public collection/patents) / phenotypic/molecular characterisation of microorganisms / identification/molecular typing of microorganisms / isolation/cultivation/preservation of microorganisms / microbial community analyses / microbial phylogenetic studies / screening/bioassays with / microorganisms / access to microbiological databases / consultancy/contract research / legal issues (e.g. Nagoya Protocol) / biosafety/biosecurity / training
Costs: Costs depend on the kind of service requested.
Access modes: Access modes depend on the kind of service requested.
Why MIRRI: MIRRI offers not only a broad spectrum of high quality microorganisms, but also a longlasting expertise in each field of microbiology. Aiming at harmonising the current microbial Biological Resource Centre (mBRC) landscape, MIRRI enables facilitated access to deposited microorganisms and is constantly improving the corresponding state-of-the-art service offers. Our experts ensure legal compliance of resources (Nagoya Protocol) and with the envisaged interoperability of existing and future databases researchers can exploit the full value of microorganisms.
Countries involved: Under development
Contact person: MIRRI Interim Secretariat
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BBMRI-ERIC is a research infrastructure of biobanks and biomolecular resources. The main goal is to provide expertise and services, advancing the use of European sample collections and its data for the benefit of human health. The activities are on a non-economic basis and primarily intended for member countries.
Services: BBMRI-ERIC delivers services to their member states in IT; Quality Management; ELSI; Biobanking Development; Public Affairs; and Outreach, Education and Communications
Costs: Services are free for those biobanks that are located in a member state.
Access modes: Access can be on-site or online, dependent on the requested service.
Why BBMRI-ERIC: Reproducible data in research is key and in order to achieve that, you need high-quality samples and data as a starting point. BBMRI-ERIC enables biobanks to work with high-quality samples and associated data and supports controlled access to the wider research community, being a true gateway to health.
Countries involved: Members: AT, BE, BG, CH, CY, CZ, DE, EE, ES, FI, GR, HU, IT, LT, LV, ML, NL, NO, PL, SE, SK, SL / Observers: DK, IARC/WHO, QA, TR
Contact person: Eleanor Shember, contact@bbmri-eric.eu
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EATRIS is the European infrastructure for translational medicine. The infrastructure brings together resources and services for research communities to translate scientific discoveries into benefits for patients.
Services: Support funding applications (Identification of partners for consortium building, assessment of the project plan’s impact and innovation potential) / Translational research facilities and expertise for development of novel biomarkers, diagnostics and therapeutics / Molecular, functional & hybrid imaging technologies, preclinical models, samples, patient cohorts, GMP manufacturing / Regulatory and Health Technology Assessment (HTA) expertise / Advice on intellectual property issues and industry partnering strategy (innovation management)
Costs: Costs are calculated on a case by case basis depending on the service required; some services can also be provided as part of funding proposals with EATRIS joining consortia as partner or subcontractor.
Access modes: Services performed can be offered either centrally by the coordination and support team based in Amsterdam or remotely by the EATRIS institutions.
Why EATRIS: Translating novel biology insights into effective interventions or medical applications is a highly complex process. It requires significant dedicated expertise, facilities and resources. We believe in your medical innovation and we want to support you by bringing together the multi-disciplinary expertise and infrastructure required for optimising your translational trajectory. Working with EATRIS gives greater confidence in the translational feasibility of your project and its impact.
Countries involved: FR, NL, CZ, HR, SE, NO, FI, IT, ES, SI, LU, LV, PO, BG
Contact person: Florence Bietrix
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ECRIN is a pan-European distributed infrastructure that links scientific partners across Europe to facilitate multinational clinical research. ECRIN provides sponsors and investigators with support for the development and implementation of multinational clinical trials.
Services: Information and advice for funding applications and preparation of multinational clinical trials (methodology, operational aspects, regulatory, ethics, contracting…) / Trial management operations (interaction with competent authorities & ethics committees, project management, monitoring, vigilance, data management) / Clinical trial tools (outcome measures, regulatory database, site locations, risk-based monitoring) / Data centre certification program (audits European, non-commercial data centres using ECRIN IT/DM standards, to confirm their ability to provide compliant, effective, and efficient data management services for controlled clinical trials)
Costs: Information and advice are free for ECRIN members. The cost of trial management services depends on the type of service requested. Data centre certification costs depend on the type of country membership.
Access modes: Users submit their proposal or request to ECRIN office; the access mode depends on proposal and needs. There are annual calls for data centre certification.
Why ECRIN: Difficulties in locating clinical trials units, fulfilling local legal, regulatory and ethical requirements, and coordinating multi-country clinical trial management deter many researchers from attempting multinational clinical trials. This means that most independent clinical trials are conducted in single centres, or multiple centres within one country. ECRIN provides a path through Europe’s fragmented health and legal systems with its pan-European infrastructure that is designed to support multinational clinical research and unlock access to patients and medical expertise.
Countries involved: FR, DE, HU, IT, NO, ES, PT, CZ, IE / Observers: CH, SK, PL
Contact person: Christine Kubiak, christine.kubiak@ecrin.org
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ELIXIR unites Europe’s leading life science organisations in managing and safeguarding the increasing volume of data being generated by publicly funded research. It coordinates, integrates and sustains bioinformatics resources across its member states and enables users in academia and industry to access services that are vital for their research.
Services: Databases / tools / Interoperibility services / Computing facilities / Training courses
Costs: Whilst there may be a charge for accessing some national compute facilities, the majority of services are free for users. For example, depositing and accessing data from databases is free, as are training courses, interoperiblity services and tools for the analsyis of data. For further information please contact us.
Access modes: Users access the services virtually (online) and directly with the resource they are interested in. No application to or access via the ELIXIR Hub is required.
Why ELIXIR: ELIXIR coordinates and develops life science resources across Europe so that researchers can more easily find, analyse and share data, exchange expertise, and implement best practices. This makes it possible for them to gain greater insights into how living organisms work.
Countries involved: EMBL, UK, SE, CH, CZ, EE, NO, NL, DK, IL, PT, FI, FR, ES, BE, IT, SI, LU, IE, DE, HU, GR / Observers: CY, AT, RO
Contact person: Andy Smith
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The European Marine Biological Research Centre (EMBRC-ERIC) is a Research Infrastructure including 29 Operators across 9 different European countries. EMBRC is dedicated for marine biology and ecology research. EMBRC offers to the scientific community, academic institutions and private companies a comprehensive set of services to study marine organisms and to give access to ecosystems. EMBRC is providing local or remote access to state-of-the-art national facilities such as renowned marine biological stations.
Services: Access to ecosystems / Marine biological resources (micro & macro, alive & fixed, wild & cultivated) / Experimental facilities / Technology platforms / E-Infrastructure, Data & services / Supporting facilities
Costs: Prices depend on the nature of the service and are available upon request.
Access modes: Through the 29 European operators, users can access the services remotely or on-site. The user has to select the service of interest, submit a proposal and he/she will receive feedback or be contacted.
Why EMBRC: Researchers should contact us in order to have access to marine ecosystems, marine biological resources and associated technological platforms for analysis.
Countries involved: BE, ES, FR, IT, GR, NO, PT, IL, UK
Contact person: info@embrc.eu
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EMPHASIS is a pan-European, distributed plant phenotyping infrastructure. EMPHASIS will focus on developing and enabling access to plant phenotyping infrastructure and provision of services essential for the analysis of crop performance with respect to structure, function, quality and interaction with the environment. It will thus support the exploitation of crop genetic diversity required for the enhancement of plant productivity and progress in plant breeding.
Services: In cooperation with EPPN2020, EMPHASIS offers access to plant phenotyping infrastructures, which includes high-throughput facilities / lean field facilities / intensive field facilities / assay development / data management
Costs: European-wide access to plant phenotyping infrastructures is currently under development in our partner project EPPN2020 and is provided via its homepage. Access will be accordingly provided by EMPHASIS once it reaches its operational phase.
Access modes: Through the 29 European operators, users can access the services remotely or on-site. The user has to select the service of interest, submit a proposal and he/she will receive feedback or be contacted.
Why EMPHASIS: EPPN2020 provides transnational access to plant phenotyping infrastructure as a basis for novel scientific approaches to quantitative plant assessment in high throughput. The installations represent a diverse set of facilities for plant phenotyping in Europe with focus on: i) non-invasive high-throughput phenotyping under controlled conditions, ii) destructive sampling aiming at assessing underlying traits helping to understand the genetic variability of different plant processes, iii) controlled field facilities allowing users to control rainfall and/or the concentration of air CO2 together with high-definition, non-invasive sensors. Transnational access will be available based on a simple and transparent access procedure.
Countries involved: Preparatory phase of the project: BE, FR, IT, NL, UK, DE
Contact person: Dr. Roland Pieruschka, Dr. Sven Fahrner
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ERINHA is a pan-European distributed life sciences research Infrastructure dedicated to the study of highly infectious emerging and re-emerging high-consequence pathogens (RG4 & unknown). It brings together leading European high containment and complementary research facilities and expertise required to perform cutting-edge research on highly infectious diseases. ERINHA provides access to its state of art BSL-4 laboratories and complementary capacities and expertise to perform excellence orientated in-vitro and in-vivo research projects, trainings and advise. A wide range of capabilities and functions from high basic research laboratory capacities to NHP modeling research are provided by ERINHA, as well as expertise of senior scientists and access to complementary functions (from BSL1 to BSL4, genomics, proteomics etc.). ERINHA produces the ideal environment to facilitate coordination of research on high-consequence pathogens in Europe. The infrastructure will contribute to the enhancement of the European and global capacity, capability and emergency preparedness in the response to global outbreaks. Since 2018, ERINHA has been granted landmark status by the European Strategy Forum on Research Infrastructures (ESFRI).
Services: Access to state of art European high containment (BSL4 & BSL3) and complementary facilities to advance research on high-consequence pathogens / In-vivo testing with a variety of animal models (including small rodents, ferrets, and non-human primates) / In-vitro experiments using highly pathogenic agents with both in-person and remote access possibilities. / Project coordination and management of large scale research programmes on high consequence pathogens / Training (General Biosecurity Training; Operations of a Biosafety Laboratory; Training for potential users) / Advice and scientific expertise provider (RG4 pathogens research, containment facilities construction, biosafety/biosecurity issues, sample transport etc.) / Access to pathogens specimens
Costs: For access costs information contact ERINHA Central Coordinating Unit (CCU) at contact@erinha.eu
Access modes: ERINHA provides in-person and remote access to its services. Projects can be submitted by academic, public and industrial users. For more information contact ERINHA CCU at contact@erinha.eu
Why ERINHA: The 2014-2015 Ebola outbreak and cases in Europe demonstrated the worldwide vulnerability and need for common action putting together rare high containment capacities and expertise to be able to increase European and global preparedness for outbreaks of high consequence pathogens. ERINHA facilitates access to required infrastructure capacities thanks to its CCU and multiple high containment and complementary European resources. It is a unique coordinated infrastrucuture providing transnational access to its facilities, large scope of services and shorter delays in access.
Countries involved: Austria (Medical University of Graz), Belgium (KUL), France (Inserm), Hungary (Ministry of Human Capacities), Netherlands (ERASMUS MC), Portugal (INSA), Spain (Instituto de Salud Carlos III), Sweden (FOHM)
Contact person: Diana Stepanyan-Yerdamian, Dylan Bonfils, contact@erinha.eu
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EU-OPENSCREEN integrates high-capacity screening platforms throughout Europe, which jointly use a rationally selected compound collection, comprising up to 140.000 commercial and proprietary compounds collected from European chemists. EU-OPENSCREEN offers to researchers from academic institutions, SMEs and industrial organisations open access to its shared resources. EU-OPENSCREEN will collaboratively develop novel molecular tool compounds with external users from various disciplines of the life sciences.
Services: High-throughput compound/ drug screening (HTS) / access to a unique European compound collection (> 100,000 compounds) / assay adaption / chemical optimization and profiling of preliminary ‘hits’ / bioprofiling of donated compounds / provision of standardised data / training and education activities
Costs: A screening project at a typical EU-OPENSCREEN screening site will cost 50-250k €, strongly depending on the number of screened substances and the maturity/ complexity of the assay. A compound replenishment fee structure applies to all projects using the EU-OPENSCREEN compound collection and users from countries which are members of the EU-OPENSCREEN ERIC will receive a discount on this cost.
Access modes: Users are requested to submit project proposal to the EU-OPENSCREEN office. Depending on the project requirements, the RI can be assessed remotely or on-site.
Why EU-OPENSCREEN: The majority of scientists in Europe do not have access to suitable technology platforms and compound collections, which are generally expensive to purchase, operate and maintain. As a large-scale research infrastructure (RI) with an ‘open’ pre-competitive character, EU-OPENSCREEN will cost-effectively overcome this limitation by: involving and providing access to Europe’s leading screening platforms and chemistry groups; offering a jointly used rationally designed compound collection; and operating an open-access bioactivity database which will be accessible on a global basis. EU-OPENSCREEN offers to support you through grant application processes and beyond for funding involving screening projects.
Countries involved: CZ, FI, DE, LV, NO, PO, ES, DK
Contact person: Project Manager: Dr. Tanja Miletic
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Euro-BioImaging offers life scientists open access to imaging instruments, expertise, training opportunities, and data management services that they do not find at their home institutions or among their collaboration partners. All scientists, regardless of affiliation, area of expertise, or field of activity, can benefit from these pan-European open access services.
Services: Euro-BioImaging offers state-of-the-art imaging services through its internationally renowned facilities, called Nodes. Nodes cover the whole spectrum of biological and biomedical imaging, with an ever-growing portfolio of cutting-edge instruments. Researchers at any stage of their career can request access to over 45+ imaging technologies hosted at 33 Nodes located in 16 European countries and at EMBL. New technologies are included continuously to offer access to the most innovative and pioneering technologies on the market.
Costs: The access fees for each visit are individually discussed and agreed upon directly between the Euro-BioImaging user and the respective Euro-BioImaging Node as part of the pre-visit discussion during the project planning phase. The user is therefore fully informed of all costs that will arise related to the access to a Euro-BioImaging Node. The Euro-BioImaging Hub, taking care of all administrative work in Euro-BioImaging, do not charge any costs to the users! Access support for users is announced on the Euro-BioImaging Web Portal.
Access modes: Euro-BioImaging offers open access to its technology portfolio, which is put in place using a selection procedure based on scientific soundness and technical feasibility of the project. In most cases, scientists visit the requested Node to perform their experiments on-site, being supported throughout their project by expert technical staff. Access to the image data resources are remote, online and can be found via the Euro-BioImaging Web Portal.
Why Euro-BioImaging: All scientists, regardless of affiliation, area of expertise, or field of activity, can benefit from Euro-BioImaging’s pan-European open access services. For most technologies, scientists are invited to receive hands-on training at the imaging instrument of their choice so that they can generate the desired data sets themselves and expand their technological knowledge. Visits can vary in length between single days to several weeks or months, depending on the project’s need and individual circumstances. Scientists interested in accessing Euro BioImaging services simply submit a short description of their planned experiment via the online application portal. Senior scientists and Node staff will offer expert advice on the project’s scope and experimental set-up to ensure that the experiment has the best chance of success from the very first visit.
Countries involved: Austria, Bulgaria, Czech Republic, Denmark, Finland, France, Hungary, Israel, Italy , Norway, Poland, Portugal, Slovenia, Sweden, The Netherlands, United Kingdom, EMBL (intergovernmental organisation), Belgium (observer)
Contact person: Johanna Bischof, Alessandra Viale
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INFRAFRONTIER is the European research infrastructure for the development, phenotyping, archiving and distribution of model mammalian genomes. It is formed by more than 25 research centres in 14 European countries and Canada. In INFRAFRONTIER these partners join forces to commonly advance the basic understanding of human health and disease using mouse and rodent models.
Services: Archiving and distribution of scientifically valuable mutant mouse strains / Rodent model development (mouse and rat) using gene targeting in embryonic ES-cells or CRISPR/CAS9 technologies/ Systemic phenotyping of mutant mice for a whole-organism view on gene function / Germ-free (axenic) mice/ Validated genetically engineered mouse models of cancer / Access to comprehensinve expertise and training
Costs: Some of the INFRAFRONTIER resources and services are provided free of charge, others entail user fees to recover costs. There are periodic Open Calls to fund researchers, for detailed information see the INFRAFRONTIER website.
Access modes: Access modalities vary with the kind of resource or service requested.
Why INFRAFRONTIER: INFRAFRONTIER provides access to unique resources and expertise to advance the understanding of human health and disease using mammalian models. Our users can rely on highest quality standards and long-standing experience. INFRAFRONTIER’s one-stop-shop facilitates efficient research.
Countries involved: DE, GR, FI, CZ, FR, EMBL
Contact person: INFRAFRONTIER Scientific User Support
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Instruct-ERIC is a pan-European research infrastructure in structural biology, making high-end technologies and methods available to scientists. Access is provided free for academic scientists at Instruct centres and includes expert support.
Services: Sample Preparation (Crystallisation, Nanobody Discovery, Protein Production) / Biomolecular Analysis (Imaging, Mass Spectrometry, Molecular Biophysics) / 3D Structural Analysis (Electron Microscopy, Magnetic Resonance Techniques, X-ray Techniques) / Compuational Services for Structural Biology (Bioinformatics Tools, Integrative Modelling, Crystallography, Electron Microscopy, NMR)
Costs: Free for academic users; on service-basis for commercial use (user access is on a fee for service basis; no obligation to disclose or publish data). Users can apply for travel and accommodation costs where a physical visit to an Instruct facility is required.
Access modes: Depending on the requested service, access can be on-site, remote, or mail-in sample.
Why Instruct-ERIC: Instruct is at the cutting edge of new technologies: automation, remote access, new detector methods, advanced imaging. Access to Instruct-ERIC infrastructure can help advance your research – more than 1200 peer-reviewed scientific publications acknowledge Instruct.
Countries involved: BE, CZ, EMBL, FI, FR, DE, GR, IL, IT, LV, LT, NL, PT, SK, SI, ES, UK
Contact person: Dr. Claudia Alen Amaro, Coordinator Head of Operations
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MIRRI is the pan-European research infrastructure for microbial resources [i.e. bacteria (including cyanobacteria), archaea, fungi, yeasts, plant viruses, bacteriophages and their isolated DNA]. In addition, the MIRRI repertoire also covers human, animal and plant cell cultures. By provision of high quality microorganisms, associated data and the broad expertise of our partners, MIRRI aims to support research and development in the field of biotechnology.
Services: Access to microorganisms/cell lines deposited in public collections / deposit of microorganisms/cell lines (public collection/patents) / phenotypic/molecular characterisation of microorganisms / identification/molecular typing of microorganisms / isolation/cultivation/preservation of microorganisms / microbial community analyses / microbial phylogenetic studies / screening/bioassays with / microorganisms / access to microbiological databases / consultancy/contract research / legal issues (e.g. Nagoya Protocol) / biosafety/biosecurity / training
Costs: Costs depend on the kind of service requested.
Access modes: Access modes depend on the kind of service requested.
Why MIRRI: MIRRI offers not only a broad spectrum of high quality microorganisms, but also a longlasting expertise in each field of microbiology. Aiming at harmonising the current microbial Biological Resource Centre (mBRC) landscape, MIRRI enables facilitated access to deposited microorganisms and is constantly improving the corresponding state-of-the-art service offers. Our experts ensure legal compliance of resources (Nagoya Protocol) and with the envisaged interoperability of existing and future databases researchers can exploit the full value of microorganisms.
Countries involved: Under development
Contact person: MIRRI Interim Secretariat
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EATRIS is the European infrastructure for translational medicine. The infrastructure brings together resources and services for research communities to translate scientific discoveries into benefits for patients.
Services: Support funding applications (Identification of partners for consortium building, assessment of the project plan’s impact and innovation potential) / Translational research facilities and expertise for development of novel biomarkers, diagnostics and therapeutics / Molecular, functional & hybrid imaging technologies, preclinical models, samples, patient cohorts, GMP manufacturing / Regulatory and Health Technology Assessment (HTA) expertise / Advice on intellectual property issues and industry partnering strategy (innovation management)
Costs: Costs are calculated on a case by case basis depending on the service required; some services can also be provided as part of funding proposals with EATRIS joining consortia as partner or subcontractor.
Access modes: Services performed can be offered either centrally by the coordination and support team based in Amsterdam or remotely by the EATRIS institutions.
Why EATRIS: Translating novel biology insights into effective interventions or medical applications is a highly complex process. It requires significant dedicated expertise, facilities and resources. We believe in your medical innovation and we want to support you by bringing together the multi-disciplinary expertise and infrastructure required for optimising your translational trajectory. Working with EATRIS gives greater confidence in the translational feasibility of your project and its impact.
Countries involved: FR, NL, CZ, HR, SE, NO, FI, IT, ES, SI, LU, LV, PO, BG
Contact person: Florence Bietrix
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BBMRI-ERIC is a research infrastructure of biobanks and biomolecular resources. The main goal is to provide expertise and services, advancing the use of European sample collections and its data for the benefit of human health. The activities are on a non-economic basis and primarily intended for member countries.
Services: BBMRI-ERIC delivers services to their member states in IT; Quality Management; ELSI; Biobanking Development; Public Affairs; and Outreach, Education and Communications
Costs: Services are free for those biobanks that are located in a member state.
Access modes: Access can be on-site or online, dependent on the requested service.
Why BBMRI-ERIC: Reproducible data in research is key and in order to achieve that, you need high-quality samples and data as a starting point. BBMRI-ERIC enables biobanks to work with high-quality samples and associated data and supports controlled access to the wider research community, being a true gateway to health.
Countries involved: Members: AT, BE, BG, CH, CY, CZ, DE, EE, ES, FI, GR, HU, IT, LT, LV, ML, NL, NO, PL, SE, SK, SL / Observers: DK, IARC/WHO, QA, TR
Contact person: Eleanor Shember, contact@bbmri-eric.eu
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ECRIN is a pan-European distributed infrastructure that links scientific partners across Europe to facilitate multinational clinical research. ECRIN provides sponsors and investigators with support for the development and implementation of multinational clinical trials.
Services: Information and advice for funding applications and preparation of multinational clinical trials (methodology, operational aspects, regulatory, ethics, contracting…) / Trial management operations (interaction with competent authorities & ethics committees, project management, monitoring, vigilance, data management) / Clinical trial tools (outcome measures, regulatory database, site locations, risk-based monitoring) / Data centre certification program (audits European, non-commercial data centres using ECRIN IT/DM standards, to confirm their ability to provide compliant, effective, and efficient data management services for controlled clinical trials)
Costs: Information and advice are free for ECRIN members. The cost of trial management services depends on the type of service requested. Data centre certification costs depend on the type of country membership.
Access modes: Users submit their proposal or request to ECRIN office; the access mode depends on proposal and needs. There are annual calls for data centre certification.
Why ECRIN: Difficulties in locating clinical trials units, fulfilling local legal, regulatory and ethical requirements, and coordinating multi-country clinical trial management deter many researchers from attempting multinational clinical trials. This means that most independent clinical trials are conducted in single centres, or multiple centres within one country. ECRIN provides a path through Europe’s fragmented health and legal systems with its pan-European infrastructure that is designed to support multinational clinical research and unlock access to patients and medical expertise.
Countries involved: FR, DE, HU, IT, NO, ES, PT, CZ, IE / Observers: CH, SK, PL
Contact person: Christine Kubiak, christine.kubiak@ecrin.org
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MIRRI is the pan-European research infrastructure for microbial resources [i.e. bacteria (including cyanobacteria), archaea, fungi, yeasts, plant viruses, bacteriophages and their isolated DNA]. In addition, the MIRRI repertoire also covers human, animal and plant cell cultures. By provision of high quality microorganisms, associated data and the broad expertise of our partners, MIRRI aims to support research and development in the field of biotechnology.
Services: Access to microorganisms/cell lines deposited in public collections / deposit of microorganisms/cell lines (public collection/patents) / phenotypic/molecular characterisation of microorganisms / identification/molecular typing of microorganisms / isolation/cultivation/preservation of microorganisms / microbial community analyses / microbial phylogenetic studies / screening/bioassays with / microorganisms / access to microbiological databases / consultancy/contract research / legal issues (e.g. Nagoya Protocol) / biosafety/biosecurity / training
Costs: Costs depend on the kind of service requested.
Access modes: Access modes depend on the kind of service requested.
Why MIRRI: MIRRI offers not only a broad spectrum of high quality microorganisms, but also a longlasting expertise in each field of microbiology. Aiming at harmonising the current microbial Biological Resource Centre (mBRC) landscape, MIRRI enables facilitated access to deposited microorganisms and is constantly improving the corresponding state-of-the-art service offers. Our experts ensure legal compliance of resources (Nagoya Protocol) and with the envisaged interoperability of existing and future databases researchers can exploit the full value of microorganisms.
Countries involved: Under development
Contact person: MIRRI Interim Secretariat
The following RIs offer complementary services
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EATRIS is the European infrastructure for translational medicine. The infrastructure brings together resources and services for research communities to translate scientific discoveries into benefits for patients.
Services: Support funding applications (Identification of partners for consortium building, assessment of the project plan’s impact and innovation potential) / Translational research facilities and expertise for development of novel biomarkers, diagnostics and therapeutics / Molecular, functional & hybrid imaging technologies, preclinical models, samples, patient cohorts, GMP manufacturing / Regulatory and Health Technology Assessment (HTA) expertise / Advice on intellectual property issues and industry partnering strategy (innovation management)
Costs: Costs are calculated on a case by case basis depending on the service required; some services can also be provided as part of funding proposals with EATRIS joining consortia as partner or subcontractor.
Access modes: Services performed can be offered either centrally by the coordination and support team based in Amsterdam or remotely by the EATRIS institutions.
Why EATRIS: Translating novel biology insights into effective interventions or medical applications is a highly complex process. It requires significant dedicated expertise, facilities and resources. We believe in your medical innovation and we want to support you by bringing together the multi-disciplinary expertise and infrastructure required for optimising your translational trajectory. Working with EATRIS gives greater confidence in the translational feasibility of your project and its impact.
Countries involved: FR, NL, CZ, HR, SE, NO, FI, IT, ES, SI, LU, LV, PO, BG
Contact person: Florence Bietrix
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The European Marine Biological Research Centre (EMBRC-ERIC) is a Research Infrastructure including 29 Operators across 9 different European countries. EMBRC is dedicated for marine biology and ecology research. EMBRC offers to the scientific community, academic institutions and private companies a comprehensive set of services to study marine organisms and to give access to ecosystems. EMBRC is providing local or remote access to state-of-the-art national facilities such as renowned marine biological stations.
Services: Access to ecosystems / Marine biological resources (micro & macro, alive & fixed, wild & cultivated) / Experimental facilities / Technology platforms / E-Infrastructure, Data & services / Supporting facilities
Costs: Prices depend on the nature of the service and are available upon request.
Access modes: Through the 29 European operators, users can access the services remotely or on-site. The user has to select the service of interest, submit a proposal and he/she will receive feedback or be contacted.
Why EMBRC: Researchers should contact us in order to have access to marine ecosystems, marine biological resources and associated technological platforms for analysis.
Countries involved: BE, ES, FR, IT, GR, NO, PT, IL, UK
Contact person: info@embrc.eu
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EMPHASIS is a pan-European, distributed plant phenotyping infrastructure. EMPHASIS will focus on developing and enabling access to plant phenotyping infrastructure and provision of services essential for the analysis of crop performance with respect to structure, function, quality and interaction with the environment. It will thus support the exploitation of crop genetic diversity required for the enhancement of plant productivity and progress in plant breeding.
Services: In cooperation with EPPN2020, EMPHASIS offers access to plant phenotyping infrastructures, which includes high-throughput facilities / lean field facilities / intensive field facilities / assay development / data management
Costs: European-wide access to plant phenotyping infrastructures is currently under development in our partner project EPPN2020 and is provided via its homepage. Access will be accordingly provided by EMPHASIS once it reaches its operational phase.
Access modes: Through the 29 European operators, users can access the services remotely or on-site. The user has to select the service of interest, submit a proposal and he/she will receive feedback or be contacted.
Why EMPHASIS: EPPN2020 provides transnational access to plant phenotyping infrastructure as a basis for novel scientific approaches to quantitative plant assessment in high throughput. The installations represent a diverse set of facilities for plant phenotyping in Europe with focus on: i) non-invasive high-throughput phenotyping under controlled conditions, ii) destructive sampling aiming at assessing underlying traits helping to understand the genetic variability of different plant processes, iii) controlled field facilities allowing users to control rainfall and/or the concentration of air CO2 together with high-definition, non-invasive sensors. Transnational access will be available based on a simple and transparent access procedure.
Countries involved: Preparatory phase of the project: BE, FR, IT, NL, UK, DE
Contact person: Dr. Roland Pieruschka, Dr. Sven Fahrner
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EATRIS is the European infrastructure for translational medicine. The infrastructure brings together resources and services for research communities to translate scientific discoveries into benefits for patients.
Services: Support funding applications (Identification of partners for consortium building, assessment of the project plan’s impact and innovation potential) / Translational research facilities and expertise for development of novel biomarkers, diagnostics and therapeutics / Molecular, functional & hybrid imaging technologies, preclinical models, samples, patient cohorts, GMP manufacturing / Regulatory and Health Technology Assessment (HTA) expertise / Advice on intellectual property issues and industry partnering strategy (innovation management)
Costs: Costs are calculated on a case by case basis depending on the service required; some services can also be provided as part of funding proposals with EATRIS joining consortia as partner or subcontractor.
Access modes: Services performed can be offered either centrally by the coordination and support team based in Amsterdam or remotely by the EATRIS institutions.
Why EATRIS: Translating novel biology insights into effective interventions or medical applications is a highly complex process. It requires significant dedicated expertise, facilities and resources. We believe in your medical innovation and we want to support you by bringing together the multi-disciplinary expertise and infrastructure required for optimising your translational trajectory. Working with EATRIS gives greater confidence in the translational feasibility of your project and its impact.
Countries involved: FR, NL, CZ, HR, SE, NO, FI, IT, ES, SI, LU, LV, PO, BG
Contact person: Florence Bietrix
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INFRAFRONTIER is the European research infrastructure for the development, phenotyping, archiving and distribution of model mammalian genomes. It is formed by more than 25 research centres in 14 European countries and Canada. In INFRAFRONTIER these partners join forces to commonly advance the basic understanding of human health and disease using mouse and rodent models.
Services: Archiving and distribution of scientifically valuable mutant mouse strains / Rodent model development (mouse and rat) using gene targeting in embryonic ES-cells or CRISPR/CAS9 technologies/ Systemic phenotyping of mutant mice for a whole-organism view on gene function / Germ-free (axenic) mice/ Validated genetically engineered mouse models of cancer / Access to comprehensinve expertise and training
Costs: Some of the INFRAFRONTIER resources and services are provided free of charge, others entail user fees to recover costs. There are periodic Open Calls to fund researchers, for detailed information see the INFRAFRONTIER website.
Access modes: Access modalities vary with the kind of resource or service requested.
Why INFRAFRONTIER: INFRAFRONTIER provides access to unique resources and expertise to advance the understanding of human health and disease using mammalian models. Our users can rely on highest quality standards and long-standing experience. INFRAFRONTIER’s one-stop-shop facilitates efficient research.
Countries involved: DE, GR, FI, CZ, FR, EMBL
Contact person: INFRAFRONTIER Scientific User Support
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ECRIN is a pan-European distributed infrastructure that links scientific partners across Europe to facilitate multinational clinical research. ECRIN provides sponsors and investigators with support for the development and implementation of multinational clinical trials.
Services: Information and advice for funding applications and preparation of multinational clinical trials (methodology, operational aspects, regulatory, ethics, contracting…) / Trial management operations (interaction with competent authorities & ethics committees, project management, monitoring, vigilance, data management) / Clinical trial tools (outcome measures, regulatory database, site locations, risk-based monitoring) / Data centre certification program (audits European, non-commercial data centres using ECRIN IT/DM standards, to confirm their ability to provide compliant, effective, and efficient data management services for controlled clinical trials)
Costs: Information and advice are free for ECRIN members. The cost of trial management services depends on the type of service requested. Data centre certification costs depend on the type of country membership.
Access modes: Users submit their proposal or request to ECRIN office; the access mode depends on proposal and needs. There are annual calls for data centre certification.
Why ECRIN: Difficulties in locating clinical trials units, fulfilling local legal, regulatory and ethical requirements, and coordinating multi-country clinical trial management deter many researchers from attempting multinational clinical trials. This means that most independent clinical trials are conducted in single centres, or multiple centres within one country. ECRIN provides a path through Europe’s fragmented health and legal systems with its pan-European infrastructure that is designed to support multinational clinical research and unlock access to patients and medical expertise.
Countries involved: FR, DE, HU, IT, NO, ES, PT, CZ, IE / Observers: CH, SK, PL
Contact person: Christine Kubiak, christine.kubiak@ecrin.org
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ERINHA is a pan-European distributed life sciences research Infrastructure dedicated to the study of highly infectious emerging and re-emerging high-consequence pathogens (RG4 & unknown). It brings together leading European high containment and complementary research facilities and expertise required to perform cutting-edge research on highly infectious diseases. ERINHA provides access to its state of art BSL-4 laboratories and complementary capacities and expertise to perform excellence orientated in-vitro and in-vivo research projects, trainings and advise. A wide range of capabilities and functions from high basic research laboratory capacities to NHP modeling research are provided by ERINHA, as well as expertise of senior scientists and access to complementary functions (from BSL1 to BSL4, genomics, proteomics etc.). ERINHA produces the ideal environment to facilitate coordination of research on high-consequence pathogens in Europe. The infrastructure will contribute to the enhancement of the European and global capacity, capability and emergency preparedness in the response to global outbreaks. Since 2018, ERINHA has been granted landmark status by the European Strategy Forum on Research Infrastructures (ESFRI).
Services: Access to state of art European high containment (BSL4 & BSL3) and complementary facilities to advance research on high-consequence pathogens / In-vivo testing with a variety of animal models (including small rodents, ferrets, and non-human primates) / In-vitro experiments using highly pathogenic agents with both in-person and remote access possibilities. / Project coordination and management of large scale research programmes on high consequence pathogens / Training (General Biosecurity Training; Operations of a Biosafety Laboratory; Training for potential users) / Advice and scientific expertise provider (RG4 pathogens research, containment facilities construction, biosafety/biosecurity issues, sample transport etc.) / Access to pathogens specimens
Costs: For access costs information contact ERINHA Central Coordinating Unit (CCU) at contact@erinha.eu
Access modes: ERINHA provides in-person and remote access to its services. Projects can be submitted by academic, public and industrial users. For more information contact ERINHA CCU at contact@erinha.eu
Why ERINHA: The 2014-2015 Ebola outbreak and cases in Europe demonstrated the worldwide vulnerability and need for common action putting together rare high containment capacities and expertise to be able to increase European and global preparedness for outbreaks of high consequence pathogens. ERINHA facilitates access to required infrastructure capacities thanks to its CCU and multiple high containment and complementary European resources. It is a unique coordinated infrastrucuture providing transnational access to its facilities, large scope of services and shorter delays in access.
Countries involved: Austria (Medical University of Graz), Belgium (KUL), France (Inserm), Hungary (Ministry of Human Capacities), Netherlands (ERASMUS MC), Portugal (INSA), Spain (Instituto de Salud Carlos III), Sweden (FOHM)
Contact person: Diana Stepanyan-Yerdamian, Dylan Bonfils, contact@erinha.eu
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EATRIS is the European infrastructure for translational medicine. The infrastructure brings together resources and services for research communities to translate scientific discoveries into benefits for patients.
Services: Support funding applications (Identification of partners for consortium building, assessment of the project plan’s impact and innovation potential) / Translational research facilities and expertise for development of novel biomarkers, diagnostics and therapeutics / Molecular, functional & hybrid imaging technologies, preclinical models, samples, patient cohorts, GMP manufacturing / Regulatory and Health Technology Assessment (HTA) expertise / Advice on intellectual property issues and industry partnering strategy (innovation management)
Costs: Costs are calculated on a case by case basis depending on the service required; some services can also be provided as part of funding proposals with EATRIS joining consortia as partner or subcontractor.
Access modes: Services performed can be offered either centrally by the coordination and support team based in Amsterdam or remotely by the EATRIS institutions.
Why EATRIS: Translating novel biology insights into effective interventions or medical applications is a highly complex process. It requires significant dedicated expertise, facilities and resources. We believe in your medical innovation and we want to support you by bringing together the multi-disciplinary expertise and infrastructure required for optimising your translational trajectory. Working with EATRIS gives greater confidence in the translational feasibility of your project and its impact.
Countries involved: FR, NL, CZ, HR, SE, NO, FI, IT, ES, SI, LU, LV, PO, BG
Contact person: Florence Bietrix
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ECRIN is a pan-European distributed infrastructure that links scientific partners across Europe to facilitate multinational clinical research. ECRIN provides sponsors and investigators with support for the development and implementation of multinational clinical trials.
Services: Information and advice for funding applications and preparation of multinational clinical trials (methodology, operational aspects, regulatory, ethics, contracting…) / Trial management operations (interaction with competent authorities & ethics committees, project management, monitoring, vigilance, data management) / Clinical trial tools (outcome measures, regulatory database, site locations, risk-based monitoring) / Data centre certification program (audits European, non-commercial data centres using ECRIN IT/DM standards, to confirm their ability to provide compliant, effective, and efficient data management services for controlled clinical trials)
Costs: Information and advice are free for ECRIN members. The cost of trial management services depends on the type of service requested. Data centre certification costs depend on the type of country membership.
Access modes: Users submit their proposal or request to ECRIN office; the access mode depends on proposal and needs. There are annual calls for data centre certification.
Why ECRIN: Difficulties in locating clinical trials units, fulfilling local legal, regulatory and ethical requirements, and coordinating multi-country clinical trial management deter many researchers from attempting multinational clinical trials. This means that most independent clinical trials are conducted in single centres, or multiple centres within one country. ECRIN provides a path through Europe’s fragmented health and legal systems with its pan-European infrastructure that is designed to support multinational clinical research and unlock access to patients and medical expertise.
Countries involved: FR, DE, HU, IT, NO, ES, PT, CZ, IE / Observers: CH, SK, PL
Contact person: Christine Kubiak, christine.kubiak@ecrin.org
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EU-OPENSCREEN integrates high-capacity screening platforms throughout Europe, which jointly use a rationally selected compound collection, comprising up to 140.000 commercial and proprietary compounds collected from European chemists. EU-OPENSCREEN offers to researchers from academic institutions, SMEs and industrial organisations open access to its shared resources. EU-OPENSCREEN will collaboratively develop novel molecular tool compounds with external users from various disciplines of the life sciences.
Services: High-throughput compound/ drug screening (HTS) / access to a unique European compound collection (> 100,000 compounds) / assay adaption / chemical optimization and profiling of preliminary ‘hits’ / bioprofiling of donated compounds / provision of standardised data / training and education activities
Costs: A screening project at a typical EU-OPENSCREEN screening site will cost 50-250k €, strongly depending on the number of screened substances and the maturity/ complexity of the assay. A compound replenishment fee structure applies to all projects using the EU-OPENSCREEN compound collection and users from countries which are members of the EU-OPENSCREEN ERIC will receive a discount on this cost.
Access modes: Users are requested to submit project proposal to the EU-OPENSCREEN office. Depending on the project requirements, the RI can be assessed remotely or on-site.
Why EU-OPENSCREEN: The majority of scientists in Europe do not have access to suitable technology platforms and compound collections, which are generally expensive to purchase, operate and maintain. As a large-scale research infrastructure (RI) with an ‘open’ pre-competitive character, EU-OPENSCREEN will cost-effectively overcome this limitation by: involving and providing access to Europe’s leading screening platforms and chemistry groups; offering a jointly used rationally designed compound collection; and operating an open-access bioactivity database which will be accessible on a global basis. EU-OPENSCREEN offers to support you through grant application processes and beyond for funding involving screening projects.
Countries involved: CZ, FI, DE, LV, NO, PO, ES, DK
Contact person: Project Manager: Dr. Tanja Miletic
The following RIs offer complementary services
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EMPHASIS is a pan-European, distributed plant phenotyping infrastructure. EMPHASIS will focus on developing and enabling access to plant phenotyping infrastructure and provision of services essential for the analysis of crop performance with respect to structure, function, quality and interaction with the environment. It will thus support the exploitation of crop genetic diversity required for the enhancement of plant productivity and progress in plant breeding.
Services: In cooperation with EPPN2020, EMPHASIS offers access to plant phenotyping infrastructures, which includes high-throughput facilities / lean field facilities / intensive field facilities / assay development / data management
Costs: European-wide access to plant phenotyping infrastructures is currently under development in our partner project EPPN2020 and is provided via its homepage. Access will be accordingly provided by EMPHASIS once it reaches its operational phase.
Access modes: Through the 29 European operators, users can access the services remotely or on-site. The user has to select the service of interest, submit a proposal and he/she will receive feedback or be contacted.
Why EMPHASIS: EPPN2020 provides transnational access to plant phenotyping infrastructure as a basis for novel scientific approaches to quantitative plant assessment in high throughput. The installations represent a diverse set of facilities for plant phenotyping in Europe with focus on: i) non-invasive high-throughput phenotyping under controlled conditions, ii) destructive sampling aiming at assessing underlying traits helping to understand the genetic variability of different plant processes, iii) controlled field facilities allowing users to control rainfall and/or the concentration of air CO2 together with high-definition, non-invasive sensors. Transnational access will be available based on a simple and transparent access procedure.
Countries involved: Preparatory phase of the project: BE, FR, IT, NL, UK, DE
Contact person: Dr. Roland Pieruschka, Dr. Sven Fahrner
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Instruct-ERIC is a pan-European research infrastructure in structural biology, making high-end technologies and methods available to scientists. Access is provided free for academic scientists at Instruct centres and includes expert support.
Services: Sample Preparation (Crystallisation, Nanobody Discovery, Protein Production) / Biomolecular Analysis (Imaging, Mass Spectrometry, Molecular Biophysics) / 3D Structural Analysis (Electron Microscopy, Magnetic Resonance Techniques, X-ray Techniques) / Compuational Services for Structural Biology (Bioinformatics Tools, Integrative Modelling, Crystallography, Electron Microscopy, NMR)
Costs: Free for academic users; on service-basis for commercial use (user access is on a fee for service basis; no obligation to disclose or publish data). Users can apply for travel and accommodation costs where a physical visit to an Instruct facility is required.
Access modes: Depending on the requested service, access can be on-site, remote, or mail-in sample.
Why Instruct-ERIC: Instruct is at the cutting edge of new technologies: automation, remote access, new detector methods, advanced imaging. Access to Instruct-ERIC infrastructure can help advance your research – more than 1200 peer-reviewed scientific publications acknowledge Instruct.
Countries involved: BE, CZ, EMBL, FI, FR, DE, GR, IL, IT, LV, LT, NL, PT, SK, SI, ES, UK
Contact person: Dr. Claudia Alen Amaro, Coordinator Head of Operations
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BBMRI-ERIC is a research infrastructure of biobanks and biomolecular resources. The main goal is to provide expertise and services, advancing the use of European sample collections and its data for the benefit of human health. The activities are on a non-economic basis and primarily intended for member countries.
Services: BBMRI-ERIC delivers services to their member states in IT; Quality Management; ELSI; Biobanking Development; Public Affairs; and Outreach, Education and Communications
Costs: Services are free for those biobanks that are located in a member state.
Access modes: Access can be on-site or online, dependent on the requested service.
Why BBMRI-ERIC: Reproducible data in research is key and in order to achieve that, you need high-quality samples and data as a starting point. BBMRI-ERIC enables biobanks to work with high-quality samples and associated data and supports controlled access to the wider research community, being a true gateway to health.
Countries involved: Members: AT, BE, BG, CH, CY, CZ, DE, EE, ES, FI, GR, HU, IT, LT, LV, ML, NL, NO, PL, SE, SK, SL / Observers: DK, IARC/WHO, QA, TR
Contact person: Eleanor Shember, contact@bbmri-eric.eu
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EATRIS is the European infrastructure for translational medicine. The infrastructure brings together resources and services for research communities to translate scientific discoveries into benefits for patients.
Services: Support funding applications (Identification of partners for consortium building, assessment of the project plan’s impact and innovation potential) / Translational research facilities and expertise for development of novel biomarkers, diagnostics and therapeutics / Molecular, functional & hybrid imaging technologies, preclinical models, samples, patient cohorts, GMP manufacturing / Regulatory and Health Technology Assessment (HTA) expertise / Advice on intellectual property issues and industry partnering strategy (innovation management)
Costs: Costs are calculated on a case by case basis depending on the service required; some services can also be provided as part of funding proposals with EATRIS joining consortia as partner or subcontractor.
Access modes: Services performed can be offered either centrally by the coordination and support team based in Amsterdam or remotely by the EATRIS institutions.
Why EATRIS: Translating novel biology insights into effective interventions or medical applications is a highly complex process. It requires significant dedicated expertise, facilities and resources. We believe in your medical innovation and we want to support you by bringing together the multi-disciplinary expertise and infrastructure required for optimising your translational trajectory. Working with EATRIS gives greater confidence in the translational feasibility of your project and its impact.
Countries involved: FR, NL, CZ, HR, SE, NO, FI, IT, ES, SI, LU, LV, PO, BG
Contact person: Florence Bietrix
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ECRIN is a pan-European distributed infrastructure that links scientific partners across Europe to facilitate multinational clinical research. ECRIN provides sponsors and investigators with support for the development and implementation of multinational clinical trials.
Services: Information and advice for funding applications and preparation of multinational clinical trials (methodology, operational aspects, regulatory, ethics, contracting…) / Trial management operations (interaction with competent authorities & ethics committees, project management, monitoring, vigilance, data management) / Clinical trial tools (outcome measures, regulatory database, site locations, risk-based monitoring) / Data centre certification program (audits European, non-commercial data centres using ECRIN IT/DM standards, to confirm their ability to provide compliant, effective, and efficient data management services for controlled clinical trials)
Costs: Information and advice are free for ECRIN members. The cost of trial management services depends on the type of service requested. Data centre certification costs depend on the type of country membership.
Access modes: Users submit their proposal or request to ECRIN office; the access mode depends on proposal and needs. There are annual calls for data centre certification.
Why ECRIN: Difficulties in locating clinical trials units, fulfilling local legal, regulatory and ethical requirements, and coordinating multi-country clinical trial management deter many researchers from attempting multinational clinical trials. This means that most independent clinical trials are conducted in single centres, or multiple centres within one country. ECRIN provides a path through Europe’s fragmented health and legal systems with its pan-European infrastructure that is designed to support multinational clinical research and unlock access to patients and medical expertise.
Countries involved: FR, DE, HU, IT, NO, ES, PT, CZ, IE / Observers: CH, SK, PL
Contact person: Christine Kubiak, christine.kubiak@ecrin.org
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ELIXIR unites Europe’s leading life science organisations in managing and safeguarding the increasing volume of data being generated by publicly funded research. It coordinates, integrates and sustains bioinformatics resources across its member states and enables users in academia and industry to access services that are vital for their research.
Services: Databases / tools / Interoperibility services / Computing facilities / Training courses
Costs: Whilst there may be a charge for accessing some national compute facilities, the majority of services are free for users. For example, depositing and accessing data from databases is free, as are training courses, interoperiblity services and tools for the analsyis of data. For further information please contact us.
Access modes: Users access the services virtually (online) and directly with the resource they are interested in. No application to or access via the ELIXIR Hub is required.
Why ELIXIR: ELIXIR coordinates and develops life science resources across Europe so that researchers can more easily find, analyse and share data, exchange expertise, and implement best practices. This makes it possible for them to gain greater insights into how living organisms work.
Countries involved: EMBL, UK, SE, CH, CZ, EE, NO, NL, DK, IL, PT, FI, FR, ES, BE, IT, SI, LU, IE, DE, HU, GR / Observers: CY, AT, RO
Contact person: Andy Smith
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The European Marine Biological Research Centre (EMBRC-ERIC) is a Research Infrastructure including 29 Operators across 9 different European countries. EMBRC is dedicated for marine biology and ecology research. EMBRC offers to the scientific community, academic institutions and private companies a comprehensive set of services to study marine organisms and to give access to ecosystems. EMBRC is providing local or remote access to state-of-the-art national facilities such as renowned marine biological stations.
Services: Access to ecosystems / Marine biological resources (micro & macro, alive & fixed, wild & cultivated) / Experimental facilities / Technology platforms / E-Infrastructure, Data & services / Supporting facilities
Costs: Prices depend on the nature of the service and are available upon request.
Access modes: Through the 29 European operators, users can access the services remotely or on-site. The user has to select the service of interest, submit a proposal and he/she will receive feedback or be contacted.
Why EMBRC: Researchers should contact us in order to have access to marine ecosystems, marine biological resources and associated technological platforms for analysis.
Countries involved: BE, ES, FR, IT, GR, NO, PT, IL, UK
Contact person: info@embrc.eu
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EMPHASIS is a pan-European, distributed plant phenotyping infrastructure. EMPHASIS will focus on developing and enabling access to plant phenotyping infrastructure and provision of services essential for the analysis of crop performance with respect to structure, function, quality and interaction with the environment. It will thus support the exploitation of crop genetic diversity required for the enhancement of plant productivity and progress in plant breeding.
Services: In cooperation with EPPN2020, EMPHASIS offers access to plant phenotyping infrastructures, which includes high-throughput facilities / lean field facilities / intensive field facilities / assay development / data management
Costs: European-wide access to plant phenotyping infrastructures is currently under development in our partner project EPPN2020 and is provided via its homepage. Access will be accordingly provided by EMPHASIS once it reaches its operational phase.
Access modes: Through the 29 European operators, users can access the services remotely or on-site. The user has to select the service of interest, submit a proposal and he/she will receive feedback or be contacted.
Why EMPHASIS: EPPN2020 provides transnational access to plant phenotyping infrastructure as a basis for novel scientific approaches to quantitative plant assessment in high throughput. The installations represent a diverse set of facilities for plant phenotyping in Europe with focus on: i) non-invasive high-throughput phenotyping under controlled conditions, ii) destructive sampling aiming at assessing underlying traits helping to understand the genetic variability of different plant processes, iii) controlled field facilities allowing users to control rainfall and/or the concentration of air CO2 together with high-definition, non-invasive sensors. Transnational access will be available based on a simple and transparent access procedure.
Countries involved: Preparatory phase of the project: BE, FR, IT, NL, UK, DE
Contact person: Dr. Roland Pieruschka, Dr. Sven Fahrner
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ERINHA is a pan-European distributed life sciences research Infrastructure dedicated to the study of highly infectious emerging and re-emerging high-consequence pathogens (RG4 & unknown). It brings together leading European high containment and complementary research facilities and expertise required to perform cutting-edge research on highly infectious diseases. ERINHA provides access to its state of art BSL-4 laboratories and complementary capacities and expertise to perform excellence orientated in-vitro and in-vivo research projects, trainings and advise. A wide range of capabilities and functions from high basic research laboratory capacities to NHP modeling research are provided by ERINHA, as well as expertise of senior scientists and access to complementary functions (from BSL1 to BSL4, genomics, proteomics etc.). ERINHA produces the ideal environment to facilitate coordination of research on high-consequence pathogens in Europe. The infrastructure will contribute to the enhancement of the European and global capacity, capability and emergency preparedness in the response to global outbreaks. Since 2018, ERINHA has been granted landmark status by the European Strategy Forum on Research Infrastructures (ESFRI).
Services: Access to state of art European high containment (BSL4 & BSL3) and complementary facilities to advance research on high-consequence pathogens / In-vivo testing with a variety of animal models (including small rodents, ferrets, and non-human primates) / In-vitro experiments using highly pathogenic agents with both in-person and remote access possibilities. / Project coordination and management of large scale research programmes on high consequence pathogens / Training (General Biosecurity Training; Operations of a Biosafety Laboratory; Training for potential users) / Advice and scientific expertise provider (RG4 pathogens research, containment facilities construction, biosafety/biosecurity issues, sample transport etc.) / Access to pathogens specimens
Costs: For access costs information contact ERINHA Central Coordinating Unit (CCU) at contact@erinha.eu
Access modes: ERINHA provides in-person and remote access to its services. Projects can be submitted by academic, public and industrial users. For more information contact ERINHA CCU at contact@erinha.eu
Why ERINHA: The 2014-2015 Ebola outbreak and cases in Europe demonstrated the worldwide vulnerability and need for common action putting together rare high containment capacities and expertise to be able to increase European and global preparedness for outbreaks of high consequence pathogens. ERINHA facilitates access to required infrastructure capacities thanks to its CCU and multiple high containment and complementary European resources. It is a unique coordinated infrastrucuture providing transnational access to its facilities, large scope of services and shorter delays in access.
Countries involved: Austria (Medical University of Graz), Belgium (KUL), France (Inserm), Hungary (Ministry of Human Capacities), Netherlands (ERASMUS MC), Portugal (INSA), Spain (Instituto de Salud Carlos III), Sweden (FOHM)
Contact person: Diana Stepanyan-Yerdamian, Dylan Bonfils, contact@erinha.eu
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EU-OPENSCREEN integrates high-capacity screening platforms throughout Europe, which jointly use a rationally selected compound collection, comprising up to 140.000 commercial and proprietary compounds collected from European chemists. EU-OPENSCREEN offers to researchers from academic institutions, SMEs and industrial organisations open access to its shared resources. EU-OPENSCREEN will collaboratively develop novel molecular tool compounds with external users from various disciplines of the life sciences.
Services: High-throughput compound/ drug screening (HTS) / access to a unique European compound collection (> 100,000 compounds) / assay adaption / chemical optimization and profiling of preliminary ‘hits’ / bioprofiling of donated compounds / provision of standardised data / training and education activities
Costs: A screening project at a typical EU-OPENSCREEN screening site will cost 50-250k €, strongly depending on the number of screened substances and the maturity/ complexity of the assay. A compound replenishment fee structure applies to all projects using the EU-OPENSCREEN compound collection and users from countries which are members of the EU-OPENSCREEN ERIC will receive a discount on this cost.
Access modes: Users are requested to submit project proposal to the EU-OPENSCREEN office. Depending on the project requirements, the RI can be assessed remotely or on-site.
Why EU-OPENSCREEN: The majority of scientists in Europe do not have access to suitable technology platforms and compound collections, which are generally expensive to purchase, operate and maintain. As a large-scale research infrastructure (RI) with an ‘open’ pre-competitive character, EU-OPENSCREEN will cost-effectively overcome this limitation by: involving and providing access to Europe’s leading screening platforms and chemistry groups; offering a jointly used rationally designed compound collection; and operating an open-access bioactivity database which will be accessible on a global basis. EU-OPENSCREEN offers to support you through grant application processes and beyond for funding involving screening projects.
Countries involved: CZ, FI, DE, LV, NO, PO, ES, DK
Contact person: Project Manager: Dr. Tanja Miletic
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Euro-BioImaging offers life scientists open access to imaging instruments, expertise, training opportunities, and data management services that they do not find at their home institutions or among their collaboration partners. All scientists, regardless of affiliation, area of expertise, or field of activity, can benefit from these pan-European open access services.
Services: Euro-BioImaging offers state-of-the-art imaging services through its internationally renowned facilities, called Nodes. Nodes cover the whole spectrum of biological and biomedical imaging, with an ever-growing portfolio of cutting-edge instruments. Researchers at any stage of their career can request access to over 45+ imaging technologies hosted at 33 Nodes located in 16 European countries and at EMBL. New technologies are included continuously to offer access to the most innovative and pioneering technologies on the market.
Costs: The access fees for each visit are individually discussed and agreed upon directly between the Euro-BioImaging user and the respective Euro-BioImaging Node as part of the pre-visit discussion during the project planning phase. The user is therefore fully informed of all costs that will arise related to the access to a Euro-BioImaging Node. The Euro-BioImaging Hub, taking care of all administrative work in Euro-BioImaging, do not charge any costs to the users! Access support for users is announced on the Euro-BioImaging Web Portal.
Access modes: Euro-BioImaging offers open access to its technology portfolio, which is put in place using a selection procedure based on scientific soundness and technical feasibility of the project. In most cases, scientists visit the requested Node to perform their experiments on-site, being supported throughout their project by expert technical staff. Access to the image data resources are remote, online and can be found via the Euro-BioImaging Web Portal.
Why Euro-BioImaging: All scientists, regardless of affiliation, area of expertise, or field of activity, can benefit from Euro-BioImaging’s pan-European open access services. For most technologies, scientists are invited to receive hands-on training at the imaging instrument of their choice so that they can generate the desired data sets themselves and expand their technological knowledge. Visits can vary in length between single days to several weeks or months, depending on the project’s need and individual circumstances. Scientists interested in accessing Euro BioImaging services simply submit a short description of their planned experiment via the online application portal. Senior scientists and Node staff will offer expert advice on the project’s scope and experimental set-up to ensure that the experiment has the best chance of success from the very first visit.
Countries involved: Austria, Bulgaria, Czech Republic, Denmark, Finland, France, Hungary, Israel, Italy , Norway, Poland, Portugal, Slovenia, Sweden, The Netherlands, United Kingdom, EMBL (intergovernmental organisation), Belgium (observer)
Contact person: Johanna Bischof, Alessandra Viale
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INFRAFRONTIER is the European research infrastructure for the development, phenotyping, archiving and distribution of model mammalian genomes. It is formed by more than 25 research centres in 14 European countries and Canada. In INFRAFRONTIER these partners join forces to commonly advance the basic understanding of human health and disease using mouse and rodent models.
Services: Archiving and distribution of scientifically valuable mutant mouse strains / Rodent model development (mouse and rat) using gene targeting in embryonic ES-cells or CRISPR/CAS9 technologies/ Systemic phenotyping of mutant mice for a whole-organism view on gene function / Germ-free (axenic) mice/ Validated genetically engineered mouse models of cancer / Access to comprehensinve expertise and training
Costs: Some of the INFRAFRONTIER resources and services are provided free of charge, others entail user fees to recover costs. There are periodic Open Calls to fund researchers, for detailed information see the INFRAFRONTIER website.
Access modes: Access modalities vary with the kind of resource or service requested.
Why INFRAFRONTIER: INFRAFRONTIER provides access to unique resources and expertise to advance the understanding of human health and disease using mammalian models. Our users can rely on highest quality standards and long-standing experience. INFRAFRONTIER’s one-stop-shop facilitates efficient research.
Countries involved: DE, GR, FI, CZ, FR, EMBL
Contact person: INFRAFRONTIER Scientific User Support
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Instruct-ERIC is a pan-European research infrastructure in structural biology, making high-end technologies and methods available to scientists. Access is provided free for academic scientists at Instruct centres and includes expert support.
Services: Sample Preparation (Crystallisation, Nanobody Discovery, Protein Production) / Biomolecular Analysis (Imaging, Mass Spectrometry, Molecular Biophysics) / 3D Structural Analysis (Electron Microscopy, Magnetic Resonance Techniques, X-ray Techniques) / Compuational Services for Structural Biology (Bioinformatics Tools, Integrative Modelling, Crystallography, Electron Microscopy, NMR)
Costs: Free for academic users; on service-basis for commercial use (user access is on a fee for service basis; no obligation to disclose or publish data). Users can apply for travel and accommodation costs where a physical visit to an Instruct facility is required.
Access modes: Depending on the requested service, access can be on-site, remote, or mail-in sample.
Why Instruct-ERIC: Instruct is at the cutting edge of new technologies: automation, remote access, new detector methods, advanced imaging. Access to Instruct-ERIC infrastructure can help advance your research – more than 1200 peer-reviewed scientific publications acknowledge Instruct.
Countries involved: BE, CZ, EMBL, FI, FR, DE, GR, IL, IT, LV, LT, NL, PT, SK, SI, ES, UK
Contact person: Dr. Claudia Alen Amaro, Coordinator Head of Operations
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MIRRI is the pan-European research infrastructure for microbial resources [i.e. bacteria (including cyanobacteria), archaea, fungi, yeasts, plant viruses, bacteriophages and their isolated DNA]. In addition, the MIRRI repertoire also covers human, animal and plant cell cultures. By provision of high quality microorganisms, associated data and the broad expertise of our partners, MIRRI aims to support research and development in the field of biotechnology.
Services: Access to microorganisms/cell lines deposited in public collections / deposit of microorganisms/cell lines (public collection/patents) / phenotypic/molecular characterisation of microorganisms / identification/molecular typing of microorganisms / isolation/cultivation/preservation of microorganisms / microbial community analyses / microbial phylogenetic studies / screening/bioassays with / microorganisms / access to microbiological databases / consultancy/contract research / legal issues (e.g. Nagoya Protocol) / biosafety/biosecurity / training
Costs: Costs depend on the kind of service requested.
Access modes: Access modes depend on the kind of service requested.
Why MIRRI: MIRRI offers not only a broad spectrum of high quality microorganisms, but also a longlasting expertise in each field of microbiology. Aiming at harmonising the current microbial Biological Resource Centre (mBRC) landscape, MIRRI enables facilitated access to deposited microorganisms and is constantly improving the corresponding state-of-the-art service offers. Our experts ensure legal compliance of resources (Nagoya Protocol) and with the envisaged interoperability of existing and future databases researchers can exploit the full value of microorganisms.
Countries involved: Under development
Contact person: MIRRI Interim Secretariat
Please note: Most RIs are constantly developing their portfolio of services. If you do not find the service/tool you are looking for, do not hesitate to contact the RI and ask for it!